• Welcome to the Chronicle Forums.
    Please complete your profile. The forums and the rest of www.chronofhorse.com has single sign-in, so your log in information for one will automatically work for the other. Disclaimer: The opinions expressed here are the views of the individual and do not necessarily reflect the views and opinions of The Chronicle of the Horse.

Announcement

Collapse

Forum rules and no-advertising policy

As a participant on this forum, it is your responsibility to know and follow our rules. Please read this message in its entirety.

Board Rules

1. You’re responsible for what you say.
As outlined in Section 230 of the Communications Decency Act, The Chronicle of the Horse and its affiliates, as well Jelsoft Enterprises Ltd., the developers of vBulletin, are not legally responsible for statements made in the forums.

This is a public forum viewed by a wide spectrum of people, so please be mindful of what you say and who might be reading it—details of personal disputes are likely better handled privately. While posters are legally responsible for their statements, the moderators may in their discretion remove or edit posts that violate these rules. Users have the ability to modify or delete their own messages after posting, but administrators generally will not delete posts, threads or accounts upon request.

Outright inflammatory, vulgar, harassing, malicious or otherwise inappropriate statements and criminal charges unsubstantiated by a reputable news source or legal documentation will not be tolerated and will be dealt with at the discretion of the moderators.

2. Conversations in horse-related forums should be horse-related.
The forums are a wonderful source of information and support for members of the horse community. While it’s understandably tempting to share information or search for input on other topics upon which members might have a similar level of knowledge, members must maintain the focus on horses.

3. Keep conversations productive, on topic and civil.
Discussion and disagreement are inevitable and encouraged; personal insults, diatribes and sniping comments are unproductive and unacceptable. Whether a subject is light-hearted or serious, keep posts focused on the current topic and of general interest to other participants of that thread. Utilize the private message feature or personal email where appropriate to address side topics or personal issues not related to the topic at large.

4. No advertising in the discussion forums.
Posts in the discussion forums directly or indirectly advertising horses, jobs, items or services for sale or wanted will be removed at the discretion of the moderators. Use of the private messaging feature or email addresses obtained through users’ profiles for unsolicited advertising is not permitted.

Company representatives may participate in discussions and answer questions about their products or services, or suggest their products on recent threads if they fulfill the criteria of a query. False "testimonials" provided by company affiliates posing as general consumers are not appropriate, and self-promotion of sales, ad campaigns, etc. through the discussion forums is not allowed.

Paid advertising is available on our classifieds site and through the purchase of banner ads. The tightly monitored Giveaways forum permits free listings of genuinely free horses and items available or wanted (on a limited basis). Items offered for trade are not allowed.

Advertising Policy Specifics
When in doubt of whether something you want to post constitutes advertising, please contact a moderator privately in advance for further clarification. Refer to the following points for general guidelines:

Horses – Only general discussion about the buying, leasing, selling and pricing of horses is permitted. If the post contains, or links to, the type of specific information typically found in a sales or wanted ad, and it’s related to a horse for sale, regardless of who’s selling it, it doesn’t belong in the discussion forums.

Stallions – Board members may ask for suggestions on breeding stallion recommendations. Stallion owners may reply to such queries by suggesting their own stallions, only if their horse fits the specific criteria of the original poster. Excessive promotion of a stallion by its owner or related parties is not permitted and will be addressed at the discretion of the moderators.

Services – Members may use the forums to ask for general recommendations of trainers, barns, shippers, farriers, etc., and other members may answer those requests by suggesting themselves or their company, if their services fulfill the specific criteria of the original post. Members may not solicit other members for business if it is not in response to a direct, genuine query.

Products – While members may ask for general opinions and suggestions on equipment, trailers, trucks, etc., they may not list the specific attributes for which they are in the market, as such posts serve as wanted ads.

Event Announcements – Members may post one notification of an upcoming event that may be of interest to fellow members, if the original poster does not benefit financially from the event. Such threads may not be “bumped” excessively. Premium members may post their own notices in the Event Announcements forum.

Charities/Rescues – Announcements for charitable or fundraising events can only be made for 501(c)(3) tax-exempt organizations. Special exceptions may be made, at the moderators’ discretion and direction, for board-related events or fundraising activities in extraordinary circumstances.

Occasional posts regarding horses available for adoption through IRS-registered horse rescue or placement programs are permitted in the appropriate forums, but these threads may be limited at the discretion of the moderators. Individuals may not advertise or make announcements for horses in need of rescue, placement or adoption unless the horse is available through a recognized rescue or placement agency or government-run entity or the thread fits the criteria for and is located in the Giveaways forum.

5. Do not post copyrighted photographs unless you have purchased that photo and have permission to do so.

6. Respect other members.
As members are often passionate about their beliefs and intentions can easily be misinterpreted in this type of environment, try to explore or resolve the inevitable disagreements that arise in the course of threads calmly and rationally.

If you see a post that you feel violates the rules of the board, please click the “alert” button (exclamation point inside of a triangle) in the bottom left corner of the post, which will alert ONLY the moderators to the post in question. They will then take whatever action, or no action, as deemed appropriate for the situation at their discretion. Do not air grievances regarding other posters or the moderators in the discussion forums.

Please be advised that adding another user to your “Ignore” list via your User Control Panel can be a useful tactic, which blocks posts and private messages by members whose commentary you’d rather avoid reading.

7. We have the right to reproduce statements made in the forums.
The Chronicle of the Horse may copy, quote, link to or otherwise reproduce posts, or portions of posts, in print or online for advertising or editorial purposes, if attributed to their original authors, and by posting in this forum, you hereby grant to The Chronicle of the Horse a perpetual, non-exclusive license under copyright and other rights, to do so.

8. We reserve the right to enforce and amend the rules.
The moderators may delete, edit, move or close any post or thread at any time, or refrain from doing any of the foregoing, in their discretion, and may suspend or revoke a user’s membership privileges at any time to maintain adherence to the rules and the general spirit of the forum. These rules may be amended at any time to address the current needs of the board.

Please see our full Terms of Service and Privacy Policy for more information.

Thanks for being a part of the COTH forums!

(Revised 1/26/16)
See more
See less

Interceptor off the shelves? What else to use?

Collapse
X
  • Filter
  • Time
  • Show
Clear All
new posts

  • Interceptor off the shelves? What else to use?

    I have a border collie so used Interceptor last year for heartworm preventative. My vet's office told me that it's on backorder and I can't find it online either.

    I could use Heartguard but am a little leery of using Ivermectin with a border collie. Advice is appreciated!
    "Crazy is just another point of view" Sonia Dada

  • #2
    I have a rough coated collie, and my vet said they will not be making the product anymore, in fact it hasn't been manufactured since January.

    In discussing this with my vet, I am right now trying to decide between a product called Trifexis (sp?) which includes an anti flea component, or my vet said the amount of ivermectin in Heartguard is so tiny he should be OK with that. (I should add, she herself has smooth coated collies, and tells me she's given them Heartguard all along).

    Not sure what I'm going to do. The rescue I got my collie from equated Heartguard with death, basically, but my vet is, well, a vet. What to do?
    Phoenix Farm ~ Breeding-Training-Sales
    Eventing, Dressage, Young Horses
    www.phoenixsporthorses.com
    Check out my new blog: http://califcountrymom.blogspot.com

    Comment


    • #3
      I use Trifexis for my Australian Shepherd puppy. My vet also said the amount in heartguard would probably be ok. But why risk it? I've heard of dogs dying from just licking up a little bit after the horses get wormed. The Trifexis is more expensive but I think it's about the same as if you bought topical flea preventative and I love not having an oily spot on my dog from topical flea preventative.

      Comment


      • #4
        Buy it from Pets Megastore in Australia and it's no more expensive than Interceptor. Exact same ingredient.

        http://www.pets-megastore.com.au/pan...ue-p-1652.html
        I realize that I'm generalizing here, but as is often the case when I generalize, I don't care. ~ Dave Barry

        Comment


        • #5
          I also have used Interceptor for years. Last week I was at my vet's and we were talking about it. She didn't say anything about it not being made anymore, just that the whole plant was shut down because of a problem with another drug (forget which one) but since Interceptor was made there too, it was suspended. She also said that herding breed dogs (or mixes) would be OK with Ivermectin since the amount in the heartworm meds is so small. I remember years ago when we got our Australian Shepherd, my vet at the time said herding/Collie related dogs should never be given Ivermectin. That was about 18 years ago so I guess research has advanced and veterinarians aren't as conservative about this anymore.

          However, if anyone is really worried about it, there is a DNA test to see whether dogs carry the mutant MDR1 gene (the gene that makes them sensitive to certain drugs, including Ivermectin). The test is thru Washington State University but is available to vets anywhere. Not expensive, about $70.

          http://www.vetmed.wsu.edu/depts-VCPL/FAQ.aspx

          from Washington State College of Veterinary Medicine website:

          "My dog has tested positive for the MDR1 mutation. Now that Interceptor is no longer available, what heartworm preventive product should I use for my dog?

          Any of the monthly heartworm preventives (administered at the label dose) can be used in dogs with the MDR1 mutation. We recommend avoiding the 6-month or 12-month injectable products and we prefer the single-ingredient products to the multiple ingredient products
          ."


          Although none of our dogs are of herding breeding, I do like Interceptor and hope that they resume production of it. I've used it for all of our dogs ever since we started using it for our late Aussie.

          Comment


          • #6
            How come herding dogs can't have ivermectin?

            (I actually thought it was deadly to ALL dogs...)

            Genuinely curious...as I have two BC's.
            *&*&*&*&*&*&*&*&*&*&*&*&*&*&*&
            "Show me the back of a thoroughbred horse, and I will show you my wings."
            &*&*&*&*&*&*&*&*&*&*&*&*&*&*&*&

            Comment


            • #7
              I can't give Ivermectin because my dog already has seizures... Vet put him on Trifexis (which I have now read can cause seizures... Sigh.) He is also now on Phenobarbital as the seizures have progressed to more than every few months, so I guess that is why vet was OK with Trifexis. But did say specifically not to use Heartguard.
              Not all who wander are lost.

              Comment


              • #8
                If you have one of the breeds affected by the MDR1 mutation, it's best to have them tested. Ivermectin is not the only drug that can cause a problem.

                "Approximately three of every four Collies in the United States have the mutant MDR1 gene. The frequency is about the same in France and Australia, so it is likely that most Collies worldwide have the mutation. The MDR1 mutation has also been found in Shetland Sheepdogs (Shelties). Australian Shepherds, Old English Sheepdogs, English Shepherds, German Shepherds, Long-haired Whippets, Silken Windhounds, and a variety of mixed breed dogs."

                "Drugs that have been documented to cause problems in dogs with the MDR1 mutation include:
                Acepromazine (tranquilizer and pre-anesthetic agent). In dogs with the MDR1 mutation, acepromazine tends to cause more profound and prolonged sedation. We recommend reducing the dose by 25% in dogs heterozygous for the MDR1 mutation (mutant/normal) and by 30-50% in dogs homozygous for the MDR1 mutation (mutant/mutant).
                Butorphanol (analgesic and pre-anesthetic agent). Similar to acepromazine, butorphanol tends to cause more profound and prolonged sedation in dogs with the MDR1 mutation.We recommend reducing the dose by 25% in dogs heterozygous for the MDR1 mutation (mutant/normal) and by 30-50% in dogs homozygous for the MDR1 mutation (mutant/mutant).
                Emodepside (Profender�)-is a deworming drug approved for use in cats only in the U.S., but is approved for use in dogs in some other countries. Use of this drug in dogs with the MDR1 mutation has resulted in neurological toxicity.
                Erythromycin. Erythromycin may cause neurological signs in dogs with the MDR1 mutation. A mutant/mutant collie exhibited signs of neurological toxicity after receiving erythromycin. After withdrawal of the drug, the dogs neurological signs resolved. There were no other potential causes of neurological toxicity identified in the dog.
                Ivermectin (antiparasitic agent). While the dose of ivermectin used to prevent heartworm infection is SAFE in dogs with the mutation (6 micrograms per kilogram), higher doses, such as those used for treating mange (300-600 micrograms per kilogram) will cause neurological toxicity in dogs that are homozygous for the MDR1 mutation (mutant/mutant) and can cause toxicity in dogs that are heterozygous for the mutation (mutant/normal).
                Loperamide (ImodiumTM; antidiarrheal agent). At doses used to treat diarrhea, this drug will cause neurological toxicity in dogs with the MDR1 mutation. This drug should be avoided in all dogs with the MDR1 mutation.
                Selamectin, milbemycin, and moxidectin (antaparasitic agents). Similar to ivermectin, these drugs are safe in dogs with the mutation if used for heartworm prevention at the manufacturer's recommended dose. Higher doses (generally 10-20 times higher than the heartworm prevention dose) have been documented to cause neurological toxicity in dogs with the MDR1 mutation.
                Vincristine, Vinblastine, Doxorubicin (chemotherapy agents). Based on some published and ongoing research, it appears that dogs with the MDR1 mutation are more sensitive to these drugs with regard to their likelihood of having an adverse drug reaction. Bone marrow suppression (decreased blood cell counts, particulary neutrophils) and GI toxicity (anorexia, vomiting, diarrhea) are more likely to occur at normal doses in dogs with the MDR1 mutation. To reduce the likelihood of severe toxicity in these dogs, MDR1 mutant/normal dogs should have their dose reduced by 25% while MDR1 mutant/mutant dogs should have their dose reduced by a full 50%. These patients should be closely monitored for adverse effects. "

                Comment


                • #9
                  Umm.... I've never heard a vet say you cannot do Ivermectin with a seizure pet, but I do know they generally would not reccomend Trifexis because of the proven seizure risk. It does not cause seizures directly, but lowers the threshold, making them far more likely to have breakthroughs.

                  Bold- Ivermectin IS deadly to all dogs, in the higher exposure they would get from horse dewormers etc. The amount in heartworm preventative products is so incredibly low that it does not pose a threat. There is less active product in a Heartgard chew than in a BB sized drop of paste dewormer. The concern for herding breeds is that some of them carry a genetic mutation that allows the drug to cross the blood-brain barrier(which it should not) and then the body cannot flush it back out. So over time the levels continue building up and become toxic. Thankfully there is now a test to check for this genetic defect, so it is easier now to decide what to use(and hopefully who to breed). Beats the old way, "White feet don't treat" rule......
                  You can't fix stupid.... but you can breed it!

                  Comment


                  • #10
                    My vet must have been hoarding it because he has a lot. I asked about it today (his supply) and he is still under the assumption that the plant will restart production in June.
                    Random horse pics http://www.flickr.com/photos/glfprncs/
                    Talk to me about fitness or nutrition (I'm an A.C.E. Certified Personal Trainer)!
                    My blog! http://personalsweatequity.blogspot.com/

                    Comment

                    • Original Poster

                      #11
                      Thanks for all the replies. My vet office said they carry Sentinel but it's pretty pricey. Anyone know how much the test is to detect the gene?
                      "Crazy is just another point of view" Sonia Dada

                      Comment


                      • #12
                        What about Revolution?


                        https://www.revolution4dogs.com/default.aspx?sec=Home

                        I've used it when my food allergy/intolerant/h.pylori/IBD whos knows what dog had food allergy issues and the vet advised against going the Interceptor flavor tabs.

                        Comment


                        • #13
                          I'm hoarding mine for the collie. Switched the others to Heartguard but I prefer Interceptor. I've heard that Target Pharmacies still have some, you might want to make some calls. Vet can call in a prescription.

                          Revolution is supposed to be OK for collies.

                          Comment


                          • #14
                            We switched our Springer spaniel to trifexis, and have had no problems. I like the added flea protection as I hated the spot on the neck types - our kitty likes to groom 'her' dog, so I was always afraid she would ingest doggie flea treatment.
                            If you love me let me go....

                            Comment


                            • #15
                              both my dogs were switched to Iverhart Max, and that's from a vet in ohio and in tennessee (One dog is at home, the other is at college). Might be worth looking into as its the same price point

                              Comment


                              • #16
                                Iverhart is ivermectin based, which is what I believe the OP was trying to aviod
                                You can't fix stupid.... but you can breed it!

                                Comment


                                • #17
                                  Bringing this back up since I have finally run out of Interceptor. I've tried Trifexis for my smooth collie, but it makes him sick (was feeding it with his meal- read stuffing it down his throat since he won't eat it- but made him puke within a half hour or so. No good on an empty stomach either.) and now my vet has recommended Advantage. Upon reading the insert, there is no way I would give it to my dog (4 of 5 Ivermectin-sensitive collies treated with it had to be PTS due to neural problems). I suppose I should have him tested for the genetic mutation, but he is 12 years old. I'm wondering if it's honestly worth treating him for heart worm at all at this point

                                  Comment


                                  • #18
                                    I was inquring about using Ivermection for a friend and her BC. The Neurologist I worked for (he has been around a long time) said there is not enough ivermection in Heartguard to worry about it. He even showed me some research papers. Trifexis also lowers the threashold to tolerate Ivermectin. We had a dog come in in a coma after the owners administered the dog's Trifexis then the Ivermectin it was taking to treat some form of mange.

                                    Comment


                                    • #19
                                      My older dachshund got sick after giving her Trifexis, but the vet tech had given us a dosage for dogs 20-40 lbs (she's 16 lbs) and I didn't notice until I went back and read the package insert, so it was probably more from that than the drug itself. After getting the correct weight dosage I have been giving it to my other dachshund, who's been fine, but just in case I've been giving the older dachsie Iverhart.

                                      Either way, really hope Interceptor is back again soon! My vet also thought it would be back in production in a few months.
                                      "Remain relentlessly cheerful."

                                      Graphite/Pastel Portraits

                                      Comment


                                      • #20
                                        Sentinel is supposed to be back in a couple of months. I've been using Revolution once I used up my squirreled away Interceptor.

                                        Comment

                                        Working...
                                        X