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Regumate (Update)#1

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  • Regumate (Update)#1

    I need some help. Mare is severely allergic to oxytocin. Hives and swelling of face.
    A few days ago at 252 she developed a bag and started the appropriate medicines. After 10 cc of regumate she is getting bad hives. ( one dose). I am guessing it is the regumate. What to do????

    4-7-13 Day 321 No change
    More down below..........................
    Last edited by Underthebridge; Apr. 26, 2013, 11:00 AM. Reason: update

  • #2
    Did you confirm placentitis via ultrasound? There are other methods of delivering progesterone, you could try the injectable version.
    McDowell Racing Stables

    Home Away From Home

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    • Original Poster

      #3
      Ultrasound looked good, would have to order the injectable on Monday, is that what you would do, my vet is very worried even though all looked good except for a bag, what do I do if the hives get worse. Dex or let her suffer?
      Thanks.

      Comment


      • #4
        I personally would skip the regumate altogether if the ultrasound looks ok. You would have to monitor her closely and be ready to add it in if necessary. I would do one week per month of SMZs at minimum, possibly keeping her on them until closer to her due date. Lots of decisions to make, jingles.
        McDowell Racing Stables

        Home Away From Home

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        • Original Poster

          #5
          Thank You.

          Comment


          • #6
            No advice, just sending jingles.
            Horse Show Names Free name website with over 6200 names. Want to add? PM me!

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            • #7
              Have no advice, but will keep my fingers crossed!!
              Elegant Expressions Farm

              Visit us on Facebook too !!

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              • Original Poster

                #8
                Thank you, she is still bumpy but happy :0)
                I was scared her throat would swell or something.

                Comment


                • #9
                  I went to a lecture at the New Bolton Center on The Critically Ill Foal, given by Dr. Palmer. Basically, he said that most issues with newborn foals are a result of placentitis in the mare. He also said that regumate acts more as an anti inflammatory for placentitis, not just as supplemental progesterone to keep the mare pregnant. I would try SMZ's and banamine if it were my mare.
                  Last edited by Callaway; Feb. 3, 2013, 09:17 AM.
                  Kim
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                  • Original Poster

                    #10
                    Thanks for that, hives are gone but udder is large again, I was hoping it was going down.

                    Comment


                    • #11
                      No advice, but jingling for you
                      www.juniperridgeranch.us
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                      • Original Poster

                        #12
                        Originally posted by Molly Malone View Post
                        No advice, but jingling for you
                        She went out and fell on her butt. That poor baby. She started eating dirt. Time for probiotic??? And then a drink for me?

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                        • #13
                          No Dex for a pregnant mare!!!
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                          • Original Poster

                            #14
                            Yes, and I believe especially in the last trimester, I was expecting the worse, which thankfully did not happen, only hives. Now it's time for a nap. Thanks to all.

                            Comment


                            • #15
                              Originally posted by railmom View Post
                              No Dex for a pregnant mare!!!
                              There is no reason why the mare cannot be given Dexamethasone if indicated.

                              Unlike other species, Dexamethasone has not been shown to induce abortion in the mare (dependent upon dose) and is in fact recommended to accelerate fetal development in later pregnancies involving placentitis and potential early delivery.

                              Burns, SJ (2010) Clinical Safety of Dexamethasone in Mares during Pregnancy; Equine Vet. J. 5(2):91-93

                              Related article in "The Horse" magazine by Dr. Michelle LeBlanc

                              Hope this helps.
                              Jos Mottershead
                              Equine-Reproduction.com LLC
                              EquineRepro Informational Group

                              Comment


                              • #16
                                SMZ! Can't hurt and we always do 5 days' worth minimum if we suspect anything. That's prime time for placentitis (ours that had cases all had sudden udder development at day 250-275). If you do the SMZ's and the udder reduces quickly, chances are high you're dealing with placentitis.

                                If were my mare I would start immediately but I'm not a vet... however, we've lost a foal due to not understanding the signs and taking action so it's better safe than sorry for us from now on. She should not be develping an udder at 250 days no matter what... definite sign of something. In both of ours you could not see any real issue on ultrasound, either. With one mare we put her back on SMZ when udder came back after the 5 days to start (day 282 it cropped up for her), and she stayed on it after day 305 until she delivered at 322. She was milk testing "ready to go" on day 314.

                                Anyway good luck and sending jingles!
                                Signature Sporthorses
                                www.signaturesporthorses.com

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                                • Original Poster

                                  #17
                                  She has been on Uniprim for 5 days, there is no change, there is less swelling in the afternoon, feed is drastically reduced and she has 5 more days of antibiotics.

                                  I don't know what to think, 59 days left,
                                  Thanks Jos, my vet will love that info.
                                  My other mare (5 weeks behind) is certainly not all flat either, but it more moves around and comes and goes.

                                  Comment

                                  • Original Poster

                                    #18
                                    Foal on April 21, everything normal except some hives, text book delivery. Milk came in after birth. I feel lucky.

                                    Comment


                                    • #19
                                      Yea!
                                      www.juniperridgeranch.us
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                                      • #20
                                        Wahoo!!! I love a happy ending!!! Congratulations!
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