• Welcome to the Chronicle Forums.
    Please complete your profile. The forums and the rest of www.chronofhorse.com has single sign-in, so your log in information for one will automatically work for the other. Disclaimer: The opinions expressed here are the views of the individual and do not necessarily reflect the views and opinions of The Chronicle of the Horse.

Announcement

Collapse

Forum rules and no-advertising policy

As a participant on this forum, it is your responsibility to know and follow our rules. Please read this message in its entirety.

Board Rules

1. You’re responsible for what you say.
As outlined in Section 230 of the Communications Decency Act, The Chronicle of the Horse and its affiliates, as well Jelsoft Enterprises Ltd., the developers of vBulletin, are not legally responsible for statements made in the forums.

This is a public forum viewed by a wide spectrum of people, so please be mindful of what you say and who might be reading it—details of personal disputes are likely better handled privately. While posters are legally responsible for their statements, the moderators may in their discretion remove or edit posts that violate these rules. Users have the ability to modify or delete their own messages after posting, but administrators generally will not delete posts, threads or accounts upon request.

Outright inflammatory, vulgar, harassing, malicious or otherwise inappropriate statements and criminal charges unsubstantiated by a reputable news source or legal documentation will not be tolerated and will be dealt with at the discretion of the moderators.

2. Conversations in horse-related forums should be horse-related.
The forums are a wonderful source of information and support for members of the horse community. While it’s understandably tempting to share information or search for input on other topics upon which members might have a similar level of knowledge, members must maintain the focus on horses.

3. Keep conversations productive, on topic and civil.
Discussion and disagreement are inevitable and encouraged; personal insults, diatribes and sniping comments are unproductive and unacceptable. Whether a subject is light-hearted or serious, keep posts focused on the current topic and of general interest to other participants of that thread. Utilize the private message feature or personal email where appropriate to address side topics or personal issues not related to the topic at large.

4. No advertising in the discussion forums.
Posts in the discussion forums directly or indirectly advertising horses, jobs, items or services for sale or wanted will be removed at the discretion of the moderators. Use of the private messaging feature or email addresses obtained through users’ profiles for unsolicited advertising is not permitted.

Company representatives may participate in discussions and answer questions about their products or services, or suggest their products on recent threads if they fulfill the criteria of a query. False "testimonials" provided by company affiliates posing as general consumers are not appropriate, and self-promotion of sales, ad campaigns, etc. through the discussion forums is not allowed.

Paid advertising is available on our classifieds site and through the purchase of banner ads. The tightly monitored Giveaways forum permits free listings of genuinely free horses and items available or wanted (on a limited basis). Items offered for trade are not allowed.

Advertising Policy Specifics
When in doubt of whether something you want to post constitutes advertising, please contact a moderator privately in advance for further clarification. Refer to the following points for general guidelines:

Horses – Only general discussion about the buying, leasing, selling and pricing of horses is permitted. If the post contains, or links to, the type of specific information typically found in a sales or wanted ad, and it’s related to a horse for sale, regardless of who’s selling it, it doesn’t belong in the discussion forums.

Stallions – Board members may ask for suggestions on breeding stallion recommendations. Stallion owners may reply to such queries by suggesting their own stallions, only if their horse fits the specific criteria of the original poster. Excessive promotion of a stallion by its owner or related parties is not permitted and will be addressed at the discretion of the moderators.

Services – Members may use the forums to ask for general recommendations of trainers, barns, shippers, farriers, etc., and other members may answer those requests by suggesting themselves or their company, if their services fulfill the specific criteria of the original post. Members may not solicit other members for business if it is not in response to a direct, genuine query.

Products – While members may ask for general opinions and suggestions on equipment, trailers, trucks, etc., they may not list the specific attributes for which they are in the market, as such posts serve as wanted ads.

Event Announcements – Members may post one notification of an upcoming event that may be of interest to fellow members, if the original poster does not benefit financially from the event. Such threads may not be “bumped” excessively. Premium members may post their own notices in the Event Announcements forum.

Charities/Rescues – Announcements for charitable or fundraising events can only be made for 501(c)(3) tax-exempt organizations. Special exceptions may be made, at the moderators’ discretion and direction, for board-related events or fundraising activities in extraordinary circumstances.

Occasional posts regarding horses available for adoption through IRS-registered horse rescue or placement programs are permitted in the appropriate forums, but these threads may be limited at the discretion of the moderators. Individuals may not advertise or make announcements for horses in need of rescue, placement or adoption unless the horse is available through a recognized rescue or placement agency or government-run entity or the thread fits the criteria for and is located in the Giveaways forum.

5. Do not post copyrighted photographs unless you have purchased that photo and have permission to do so.

6. Respect other members.
As members are often passionate about their beliefs and intentions can easily be misinterpreted in this type of environment, try to explore or resolve the inevitable disagreements that arise in the course of threads calmly and rationally.

If you see a post that you feel violates the rules of the board, please click the “alert” button (exclamation point inside of a triangle) in the bottom left corner of the post, which will alert ONLY the moderators to the post in question. They will then take whatever action, or no action, as deemed appropriate for the situation at their discretion. Do not air grievances regarding other posters or the moderators in the discussion forums.

Please be advised that adding another user to your “Ignore” list via your User Control Panel can be a useful tactic, which blocks posts and private messages by members whose commentary you’d rather avoid reading.

7. We have the right to reproduce statements made in the forums.
The Chronicle of the Horse may copy, quote, link to or otherwise reproduce posts, or portions of posts, in print or online for advertising or editorial purposes, if attributed to their original authors, and by posting in this forum, you hereby grant to The Chronicle of the Horse a perpetual, non-exclusive license under copyright and other rights, to do so.

8. We reserve the right to enforce and amend the rules.
The moderators may delete, edit, move or close any post or thread at any time, or refrain from doing any of the foregoing, in their discretion, and may suspend or revoke a user’s membership privileges at any time to maintain adherence to the rules and the general spirit of the forum. These rules may be amended at any time to address the current needs of the board.

Please see our full Terms of Service and Privacy Policy for more information.

Thanks for being a part of the COTH forums!

(Revised 1/26/16)
See more
See less

Depo Provera/Medroxyprogesterone questions

Collapse
X
  • Filter
  • Time
  • Show
Clear All
new posts

  • Depo Provera/Medroxyprogesterone questions

    Wanted to try this on a couple of geldings and a couple of mares. Geldings who are studdy (like mounting mares, very dominant behaviour with horses and people, spooky and very reactive under saddle) and mares that are super grumpy, don't want to work while in season.

    Vet says that Depo does NOT work at all in a lot of mares and I've read some studies to that effect. I'm not particularly trying to keep them from cycling, I'm looking to alleviate the personality symptoms.

    He does say it works well in geldings and recommended it.

    I ended up buying a bottle of 200mg/ml online as it was a lot cheaper than getting it from the vet. But I'm a bit embarrassed now to ask for dosages from him as I don't want to tick him off that I bought it elsewhere.

    So could anyone relate what dosage they find effective for geldings and for mares and what bodyweight they are dosing and how frequently? A couple are horses and a couple are ponies. I've done an exhaustive search online but can't seem to narrow down dosages.

    And how have you found the effects for both mares and for geldings?

    TIA

  • #2
    I find it works better on the geldings and my vet told me to start with 6cc and redose if no change in a week, I give most 10cc a month.
    www.millcreekfarm.net
    **RIP Kickstart aka Char 12/2/2009**

    Comment


    • #3
      My mare gets 10 cc about every 3.5-4 weeks.

      Where did you get a good price and how much? always looking to save a couple bucks.

      Comment


      • #4
        I find it astonishing that you would ask this kind of question on an internet forum.

        Any hormones need to be handled with extreme care by humans, and should be administered only under direct veterinary supervision.

        That is completely aside from the question of why you are experiencing behavior problems with an entire group of horses, both mares AND geldings. Maybe a management problem, rather than a hormonal one?
        Last edited by M. O'Connor; Apr. 23, 2012, 12:59 PM.

        Inner Bay Equestrian
        Facebook
        KERx

        Comment


        • #5
          I give my gelding 10cc's of 200mg/ml once a month IM ...and I also like giving Mare Magic(raspberry leaves to both the mares and geldings that need it)

          I haven't given depo to my mares as they don't seem to need it...however I've heard that ReguMate comes in injectable form and works a lot better than depo in some cases for mares...much more expensive though I believe

          Comment


          • #6
            I'd discuss this with your vet. Explain to him you bought it cheaper and why. But he/she needs to know your horses are on it. And they can assist you with the dosing way more accurately than strangers on a forum. I would also be very very careful looking on the internet. You may be finding non reputable sources or papers that are using it for different reasons and so are using extreme doses.

            And hopefully you got the actual meds from a good place where you can actually feel comfortable using the products.

            Comment


            • #7
              Originally posted by M. O'Connor View Post
              I find it astonishing that you would ask this kind of question on an internet forum.
              And equally astonishing are the replies with recommended dosings for horses they've not examined.

              Comment


              • #8
                You all are right....

                Comment


                • #9
                  To be accurate other posters have only stated the dosage their horse are getting I do not think anyone has recommended a dosage for OP.

                  Comment


                  • #10
                    Originally posted by omare View Post
                    To be accurate other posters have only stated the dosage their horse are getting I do not think anyone has recommended a dosage for OP.
                    And you are exactly right! This BB always brings out the interesting side of some personalities! Those that have had GREAT success with using some of these pharmaceuticals after they are endorsed by a currently licensed Vet are willing to share what has worked on many different horses at different times of the year, in different situations, for different reasons, at different concentrations of active ingredients, and at different dosages. MOA of what you are giving, potential AE's, and risk vs benefit.....some of the many details to be knowledgable of, and that goes for PO, IM, IV and all other routes of administration.

                    Comment


                    • #11
                      The dosages are all given in "cc" and I would like to also point out that depending on the concentration (mg/mL) that the compounding pharmacy makes the product at - one horses "10cc" dose might not be the same as another's as far as actual miligram dose amount delivered by that volume.

                      When it comes to medications, a volume (cc or mL) is rarely an appropriate unit to communicate a dose in as far as being clear and safe.

                      Comment


                      • #12
                        Why not just seperated the mares and the geldings? Mounting problem solved. As far as the rest, your vet did not recommend it for your mares but now you're looking to an Internet bb to tell you what dose to use for them? Maybe the mares are pissy because they're tired of having geldin mounting them all the time. Maybe they have a legitimate reason to feel like crap when they're cycling. Trying to just mask the behavioral issues without treatin the underlying problems isn't fair to them and will likely bite you in the behind in the long run.
                        You can't fix stupid.... but you can breed it!

                        Comment


                        • #13
                          Originally posted by rockfordbuckeye View Post
                          The dosages are all given in "cc" and I would like to also point out that depending on the concentration (mg/mL) that the compounding pharmacy makes the product at - one horses "10cc" dose might not be the same as another's as far as actual miligram dose amount delivered by that volume.

                          When it comes to medications, a volume (cc or mL) is rarely an appropriate unit to communicate a dose in as far as being clear and safe.
                          Absolutely! How about the example of the big stars twins in a big name hospital being given the wrong dose of heparin by mistake. Medication error big time. Gave huge overdose because there are enormous differences in concentrations of heparin in vials and someone didn't read a label and gave babies x volume of x concentration when it should have been x volume of y concentration.....but, the med the op asks about is pretty benign and with proper vet advice will need trial and adjustment to get the right dosage on board. Take everyone's opinions on this board for what they are...opinions!

                          Comment


                          • #14
                            The OP hopes what was received was accurately manufactured-refer to the horrible polo pony incident of a couple years ago to see how that can go tragically wrong.
                            Last edited by M. O'Connor; Apr. 23, 2012, 12:59 PM.

                            Inner Bay Equestrian
                            Facebook
                            KERx

                            Comment


                            • #15
                              The dosages are all given in "cc" and I would like to also point out that depending on the concentration (mg/mL) that the compounding pharmacy makes the product at - one horses "10cc" dose might not be the same as another's as far as actual miligram dose amount delivered by that volume.
                              It comes in 10 and 20ml concentration (?) doses so that makes the injectiable amount diffent by 50% and the cost.

                              Prescription not needed and no special handling instructions since you don't physical come into contact unless you have an accident. It is an IM injection. As far as messing with hormones giveing Medroxyprogesterone to a gelding there really isn't any long term harm for making them aggressive and good potential for a nicer minded horse. I sure wouldn't use it on a mare.

                              I have used Reguamte on Stallions in 1/2 doeses to settle the libido for showing and know "Fact" some Breeding Farms routinly use it in non breeding season for same. It has been tested and proven NOT to affect fertility and ceasing use will quickly return horses libido to normal.

                              I with Vets full knowled will use Medroxyprogesterone AFTER castration to help settle a horse into gelding mode with excellant tried and true results.

                              ReguMate comes in injectable form and works a lot better than depo in some cases for mares...much more expensive though I believe
                              If I remember the correct name is Altergest its a 1cc IM injection weekly or every 10 days depending on how your mare cycles. Its about a 6 week dose and costs approx $140 bottle but don't hold me to that it maybe $240. I haven't ordered any in 6 months and am not currently usisng it on any one. But I did like it alot, so much easier to use. And I found it way more cost effective than Regumate.

                              But I never mix my herds w/ mares and geldings they all have their own fields and w/ exception to deep winter when no one is cycling for short durations on my farm its a No No contact and we have double fence rows as well. I even try to keep mares in one barn and geldings in another. but that a luxory of my set up and I know not everyone can do that.

                              Comment


                              • #16
                                Originally posted by judybigredpony View Post
                                It comes in 10 and 20ml concentration (?) doses so that makes the injectiable amount diffent by 50% and the cost.
                                Concentration is not a volume alone. Concentration is the amount of actual drug (and this amount is in a weight unit like "miligram" or "gram" or "microgram") PER a volume of measurement.

                                So any given compounding pharmacy could *make* medroxyprogesterone in any particular concentration if they had a recipe for it and stability information. It could be 40mg/mL, 200mg/mL etc. So thus again I am saying a "dose" of 10cc (please use the term "mL" or mililiter instead of "CC" to be safer as the two "C's" in CC can be mistaken for zeros and lead to errors) could be anywhere from 400mg to 2000mg. Do you understand the safety issue there?

                                This is why licensed veternarians should be involved in this process. They are trained to do this and can help you safely treat your horses. If cost is an issue and you don't want to buy FROM your vet, I'm still sure any caring vet would prefer to be asked and help you with what you buy online as far as dose selection, than not be involved at all and have harm happen to an animal.

                                Comment


                                • #17
                                  Rockford I agree...mine comes from a Vet pharmacey where I have an account, and yes my Vet knows I buy it from another source since she can't buy it any cheaper herself.

                                  You do need to know the concentration to give an accurate dose though which is why I mentioned that and OP should check the bottle.
                                  If it is properly labeled and and bought from a Brand name supplier she should be OK.

                                  Its not Crack for crying out load and OP should just read the label and call the vet...he did if you read the post recommend the drug for her geldings...and ask the dosage

                                  Comment


                                  • #18
                                    Just confirmed with USEF a couple days ago that medroxy and depo are forbidden substances in geldings. FYI!
                                    "ronnie was the gifted one, victor was the brilliant intellect, and i [GM], well, i am the plodder."

                                    Comment


                                    • #19
                                      Originally posted by M. O'Connor View Post
                                      I find it astonishing that you would ask this kind of question on an internet forum.

                                      Any hormones need to be handled with extreme care by humans, and should be administered only under direct veterinary supervision.

                                      That is completely aside from the question of why you are experiencing behavior problems with an entire group of horses, both mares AND geldings. Maybe a management problem, rather than a hormonal one?
                                      Not only is the quote above right on point, but there are potential SERIOUS side effects from using Depo. I would be very careful and speak with the Vet, he is not going to care that much you bought the product somewhere else.
                                      Last edited by STA; Apr. 23, 2012, 08:22 PM. Reason: mistake
                                      http://STA551.com
                                      845-363-1875

                                      Comment


                                      • #20
                                        Originally posted by alteringwego View Post
                                        Just confirmed with USEF a couple days ago that medroxy and depo are forbidden substances in geldings. FYI!
                                        Don't think so.
                                        It is a banned drug in FEI competition for male horses but not listed in USEF's drug booklet as banned for USEF competition.
                                        Primarily used for hunters which do no run under FEI regulation.

                                        Comment

                                        Working...
                                        X