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Doxy or Oxytet treatment for lyme?

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    Doxy or Oxytet treatment for lyme?

    My 21 year old gelding was tested for lyme and the test came back today that he was positive for a chronic infection. Vet is giving me a choice between two treatment options.Gelding has mild grumpies and some floating mild lameness that I have attributed to aging issues over the years, but perhaps was due to the lyme.

    Option #1: 10 day IV Oxytet- This option will require a catheter to be inserted and IV Oxytet to be administered through it for 10 days. Gelding will be in a stall at night and anytime it rains (he typically lives outside 24/7 on pasture in a group) and on solo turnout when he can go out. And will have a band around his neck to keep the catheter in place. No riding, the reins would interfere with the catheter, but I can lunge.

    Option #2: 60 days of Doxy- powder in feed. Easier than the IV oxytet, but he is on the meds for a while. Gelding is not the best at eating meds on his feed, and I would be concerned he would stop eating and not get the meds. Also, he has a history of stomach ulcers, and I have heard Doxy is hard on the stomach. But I could ride and compete and go about life as normal while he is on it.

    I merely tested as part of a spring workup, so this is kind of bad timing. Both plans cost about the same (oxytet was cheaper, but once I count in cost for stall board and vet calls, it works out about the same). I have an event on June 11th that I already sent the check in for, so option 1 would be hard to keep him ready for that ( granted we only do beginner novice). But I am going on vacation for 4 days in there that he wouldn't be ridden anyway. And obviously his needs come before any shows I have planned

    Barn owner is fine with either treatment and is experienced giving IV, but also worries about him not eating the doxy. Obviously the doxy would be more convenient, but is the oxytet considered more effective? I don't want to have to retreat again, I would rather do what needs to be done the first time. So, anyone with experience with either treatment? Anyone know if one is more effective than the other? Any thoughts, stories or opinions welcome!!

    If it were my horse I would prefer IV oxytet and shorter treatment time. Especially if your barn manager is willing to be flexible and help you out with it.

    Originally posted by PeanutButterPony
    you can shackle your pony to a lawn chair at the long as its in a conservative color.


      My 23 y.o. Paint gelding had Lyme probably about 9 or 10 years ago. He was on powdered doxy for 45 days. He turned around after a few days and has been fine ever since. Doxy came from a compounding pharmacy via the vet, and it had some flavoring, probably peppermint. He did not have any problems eating it with grain. I had an advantage in that there was a fellow barn buddy who was there in the evenings and she gave him his dose and did not miss one. I think one problem with Lyme treatment is that too many people stop it too soon. I don't remember when I started riding him again, but it wasn't all that long. Personally I'd do the powdered doxy again.
      "With hardly any other living being can a human connect as closely over so many years as a rider can with her horse." Isabell Werth, Four Legs Move My Soul. 2019


        My horse Yo got Doxy tabs when he was first diagnosed back about 10ish years ago.
        The pills I got were coated... the redhead who hated anything in his food ate them whole with his grain, no fuss, no muss.

        Efficacy of treatment would be the deciding factor for me though... and that is not something I am familiar with. Vet had no info on that for you, esp consider s/he had his numbers in front of them [was his number huge?] ?
        Yo/Yousolong April 23rd, 1985- April 15th, 2014


          the protocol is supposed to be oxytet then followed up with doxy or minocycline. so i would go with the oxytet.


            My vet just had me do 15 days of Doxy twice a day with probiotic, this worked fine for my mare who is very picky and ulcer prone


              I just ended what was intended to be a 12 week course of doxy at 9 weeks due to what appears to be ulcers. This was a case of chronic lyme that went on for quite awhile before diagnosis, hence the extended treatment, which is a whole other story...

              Horse was maintained on probiotics and 1/4 tube ulcergard throughout and still had to stop early due to discomfort.

              Doxy was extremely tough on his hindgut throughout.

              Currently girthy, started wood chewing and went from being a pig about grain to picking at it. Anxiously hoping for a quick turn around now that we have stopped the abx and increased to full tube of ulcergard.

              If I would have had the option to do oxytet I would have gone that route, logistics just didn't work out, and then followed up with a short course of doxy after the oxytet.


                IV logistics don't work for me an this horse. Vet prescribed minocycline. Much more "bioavailable" that doxy. Used to be more expensive than doxy, but now the price of doxy has gone up, the Minocycline is competitive or cheaper.

                They are capsules, and I just mix them with her feed- she eats them without a second thought.

                chief feeder and mucker for Music, Belle and Tiara. Someone else is now feeding and mucking for Chief and Brain (both foxhunting now). Spy is gone. April 15, 1982 to Jan 10, 2019.


                  Both. We do 10 days of Oxytet followed by Doxy for 30 to 60 days.


                    I love cats, I love every single cat....
                    So anyway I am a cat lover
                    And I love to run.