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Another idea on how to use Adequan - off label of course :)

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    Another idea on how to use Adequan - off label of course :)

    What if you split each vial of Adequan to make it last longer?

    It is a known fact (according to the manufacturer) that Adequan stays in the system for 96 hours.

    So for those of you, who use it once or twice a month, would it be more beneficial to split the vial of 5 ccs into smaller amounts?

    Let's say you give 10 ccs total a month (twice a month). The total number of days it stays in your horse's system each month is 8 days.

    Would it be more useful and effective if you split your 10ccs into 1.4 cc shots and give them 7 times a month (every 4 days) to keep the supply more consistent?

    Is there a reason why each vial is 5 ccs?

    #2
    My vet, who owns cutting horses as well as being a vet told me that she tried many diffierent "approaches" to using adequan but when all was said and done the on label dosage/use is the most effective. She said she actually had read a study which explained why but sorry i cannot tell you anymore than that. Hwoever, with most meds there is a "threshold" that you must give (in terms of amount of the medication) and less than that and the body basically does not utilize it. So I would tend to say to use it as indicated
    www.shawneeacres.net

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      #3
      I suspect you'd have the same effect with thqat regimen that you would if you merely poured it down the drain.

      Serum half-life isn't a very accurate method of measuring effect.
      "It's like a Russian nesting doll of train wrecks."--CaitlinandTheBay

      ...just settin' on the Group W bench.

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        #4
        In my mind, giving 1.4 cc's of the stuff to a 1200 lb horse would be like giving a child's dose of tylenol to a 200 lb man. I think you need a certain amount of any drug in the system to actually be effective.

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          #5
          Off label use of Adequan

          I can see why you ask, but here is a thought coming from the research end of the pharmaceutical industry.
          Drug companies try VERY hard to show that their drug works, then they try VERY VERY hard to show it works well. In doing so, they tend to play around A LOT with how to best administer it to maximize good effects (and minimize side effects). They do this because there is a ton of money at stake. 99 times out of 100, if you think you've thought of some new "better" way to give a drug to make it more effective, it's been tried before and failed.

          Comment

            Original Poster

            #6
            Thank you all for your replies. Adequan is expensive, so I was trying to figure out ways to make it last longer without increasing my costs.

            Someone needs to come out with a true generic version

            Comment


              #7
              For generics. Wait till the original patent expires.

              Otherwise, I think the minimum doses and loading doses have a physiological basis. If I'm not completely full of sh!t, it has to do with saturating all chemical "gates" in cell membranes that allow stuff into and out of cells. If you don't put in enough of the stuff to control all of them, the effects of the chemical given afterward is reduced because it just passes by the still-closed-off gates.

              If you want to get all sciencey, economical and everything, you could look for studies that address minimal loading doses and their timing for Adequan.
              The armchair saddler
              Politically Pro-Cat

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                #8
                I thought the patent was expired on Adequan? My vet gave me something called Ichon
                that is being referred to as generic adequan. It's much cheaper and i have had good results with it.
                "Perhaps the final test of anybody's love of dogs is their willingness to permit them to make a camping ground of the bed" -Henry T. Merwin

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                  Original Poster

                  #9
                  Originally posted by mvp View Post
                  For generics. Wait till the original patent expires.

                  Otherwise, I think the minimum doses and loading doses have a physiological basis. If I'm not completely full of sh!t, it has to do with saturating all chemical "gates" in cell membranes that allow stuff into and out of cells. If you don't put in enough of the stuff to control all of them, the effects of the chemical given afterward is reduced because it just passes by the still-closed-off gates.

                  If you want to get all sciencey, economical and everything, you could look for studies that address minimal loading doses and their timing for Adequan.
                  Thanks, this helps to understand the reasoning behind not giving less than 5 ccs in each shot. I tried to find some studies on it, but so far I haven't been very successful. I'll have to google it some more!

                  And yes, I totally love getting all "sciencey" about stuff

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                    Original Poster

                    #10
                    Originally posted by Jaegermonster View Post
                    I thought the patent was expired on Adequan? My vet gave me something called Ichon
                    that is being referred to as generic adequan. It's much cheaper and i have had good results with it.
                    I've heard about Ichon, but I believe the formula is different. I'll look into it though!

                    Comment


                      #11
                      I've been pondering whether I could give a pony who's a little stiff a half-dose of adequan, since she's under 500 lb. Any thoughts?

                      Comment


                        #12
                        Originally posted by Jaegermonster View Post
                        I thought the patent was expired on Adequan? My vet gave me something called Ichon
                        that is being referred to as generic adequan. It's much cheaper and i have had good results with it.
                        The patent HAS expired, but Ichon is absolutely NOT "generic" adequan. Ichon is licensed as a wound dressing only. If you inject it IM and have an adverse reaction, you are absolutely SOL. There have been zero studies on using Ichon IM to help with joint health and there's been zero research on injecting it IM.

                        There is NO generic Adequan, unfortunately.

                        Comment


                          #13
                          Can I buy stock in Luitpold, Adequan's Daddy and Pimp. Or is it too late to get in on this cash cow?
                          The armchair saddler
                          Politically Pro-Cat

                          Comment


                            #14
                            Patent is expired on Adequan. But no other manufacturer is bothering to mimic it b/c it is a complex formula, apparently...

                            Comment


                              #15
                              Originally posted by vali View Post
                              I've been pondering whether I could give a pony who's a little stiff a half-dose of adequan, since she's under 500 lb. Any thoughts?
                              No - full dose.

                              It's not like deworming or antibiotics where it's a weight-based dose. It's more like vaccines where it simply takes X amount of the product to do Y job and it *totally* independent of weight.
                              ______________________________
                              The CoTH CYA - please consult w/your veterinarian under any and all circumstances. - ET

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