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Estrogen injections for stifle

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  • Estrogen injections for stifle

    Has anyone had experience with injecting estrogen for stifle issues? Any infor or thoughts would be greatly appreciated.

  • #2
    Esterone? Tried it, did nothing for my horse. 2 other horses at the barn used it at the same time and saw marked improvement. I think it matters a great deal WHY the stifles are problematic, and not every horse sees results. I also think it matters how frequently you inject, I don't think my horse had enough Esterone over a significant enough period.

    It also made my horse ANGRY, which is an odd side effect but one that the vet says he has heard of before.
    "The Son Dee Times" "Sustained" "Somerset" "Franklin Square"


    • #3
      Yes, good results with ECP

      I often use ECP for weak stifles. I have a two year old right now that has a stifle that locks. He gets an ECP shot every two weeks and like clockwork on around day 12 his stifle starts sticking. Give him a shot and he's perfect again.
      I deal mainly in youngstock whose stifle problems are generally weakness issues that go away as they get in shape. I find ECP very helpful with this kind.


      • #4
        My friends horse has string-halt in both stifles. She used some time of hormone therapy, can't remember what exactly, but it was injections and he made a little bit of improvement but not significantly enough to keep using it.


        • #5
          It is Esterone (sp?) not Estrogen! mY PSSMy Belgian X did not benefit from the shots!


          Rerider/Haydunker Clique

          RIP Barbaro, you were my hero!


          • #6
            Estrone is 1 of 3 types of estrogen

            Estradiol and estriol are the other 2 estrogen forms.

            At one point I researched the differences as it related to use for catching/locking stifles, and while I can't recall for sure, it seemed that estradiol was a more efficient form, but I can't remember why.
            The CoTH CYA - please consult w/your veterinarian under any and all circumstances. - ET


            • #7
              Right it is estrone which is a form of estrogen. I have seen it work virtual miracles in some horses. At worst it has no effect, at best you have a new horse.
              McDowell Racing Stables

              Home Away From Home


              • #8
                I used it for my horse who was basically sound but was a bit uneven going one direction. Vet suggested estrone to help out and build some muscle while bringing him along but I really didn't see too much improvement on both. It is relatively cheap and something to try. Worked really good on my old event horse that has sticky stifles and would lock once in awhile


                • #9
                  I did a monthly shot on a gelding who had hyper-extended his right hind stifle. It was weak/loose after that. With the estrone shots, it tightened up and he moved as he did before his injury. Plus it made him very sweet. :-)


                  • #10
                    I found it helped quite a bit with my gelding, plus it mellowed him out a little which was nice.


                    • #11
                      Yes it did seem to help my gelding with a loose stifle, however it was done in conjunction with wedge pads on his hinds. Once the pads came off he has not had the problem since.
                      A quick tutorial on interval training: Conditioning your horse for eventing


                      • #12
                        Estrone/estrogen directly binds to the ligaments causing laxity. This is how women are able give birth. The laxity enables the ligaments to stretch allowing the baby to pass through the pelvis.

                        In the case of stifles, it supposedly lets them stretch and re-align in the joint groove, reducing impingement and inflammation.

                        Studies show that women have greater chance of ligament tears when menstruating due to increased estrogen concentrations in the ligaments.



                        • #13
                          used it with great success Now I'm told estrone is no longer being made so when I do use it, I use thelan - not sure if it's the same stuff with a diff name though...


                          • #14
                            So, what is the protocol with this treatment? Is it a one time injection or several?

                            What is the recovery time, i.e. are they stalled for a certain time, how long to see full benefits?

                            For those that have done this, what was the cost approx?


                            • #15
                              Originally posted by NorCalDressage View Post
                              So, what is the protocol with this treatment? Is it a one time injection or several?
                              My vet's preferred method is 3 shots a week apart. She feels if you're going to see improvement, you'll see it by then. She doesn't have a problem with a 4th shot, especially if you're borderline seeing results - some horses might really just need more. She thinks 5 is a waste if you aren't seeing changes at 4.

                              After that, it's up to what the horse is telling you. She sees some who don't need anything beyond that. Others required weekly injections to maintain improvement, and that isn't feasible for some owners.

                              What is the recovery time, i.e. are they stalled for a certain time, how long to see full benefits?
                              Keep working, appropriate for the horse's fitness and issue.

                              For those that have done this, what was the cost approx?
                              I wanna say mine (estradiol, not estrone, IIRC) was about $10/shot, but don't quote me on that. It wasn't nearly what Adequan is, I know that, and I was surprised at how relatively inexpensive, but certainly not *cheap*, it was.
                              The CoTH CYA - please consult w/your veterinarian under any and all circumstances. - ET


                              • #16
                                Originally posted by NorCalDressage View Post
                                So, what is the protocol with this treatment? Is it a one time injection or several?

                                What is the recovery time, i.e. are they stalled for a certain time, how long to see full benefits?

                                For those that have done this, what was the cost approx?
                                Just wanted to add, it's a series of IM injections, so no recovery time/stall time like you might have with joint injections.


                                • #17
                                  I do 5ccs every other day for a total of three shots, then as needed or 10ccs as a one time pre-race dose.
                                  McDowell Racing Stables

                                  Home Away From Home


                                  • #18
                                    It's worked great on every horse I've seen it used on.


                                    • #19
                                      What do you look for in a weak stifle? How do you know if you need the injection, or is it a well let's try it thing?


                                      • #20
                                        Thanks for your responses -

                                        I guess I'm wondering, if it induces ligament laxity, aren't horses that are on this prone to other ligament injuries (esp. after reading RAyers post)?

                                        It seems some people feel this makes their horses "stronger" in the stifle or able to perform more difficult work when on the injections....I guess I'm confused....