Announcement

Collapse

Forum rules and no-advertising policy

As a participant on this forum, it is your responsibility to know and follow our rules. Please read this message in its entirety.

Board Rules

1. You're responsible for what you say.
As outlined in Section 230 of the Communications Decency Act, The Chronicle of the Horse and its affiliates, as well Jelsoft Enterprises Ltd., the developers of vBulletin, are not legally responsible for statements made in the Forums.

This is a public forum viewed by a wide spectrum of people, so please be mindful of what you say and who might be reading it--details of personal disputes may be better handled privately. While posters are legally responsible for their statements, the moderators may in their discretion remove or edit posts, though are not legally obligated to do so, regardless of content.

Users have the ability to modify or delete their own messages after posting. Moderators generally will not delete posts, threads or accounts unless they have been alerted and have determined that a post, thread or user has violated the Forums' policies. Moderators do not regularly independently monitor the Forums for such violations.

Profanity, outright vulgarity, blatant personal insults or otherwise inappropriate statements will not be tolerated and will be dealt with at the discretion of the moderators.

Users may provide their positive or negative experiences with or opinions of companies, products, individuals, etc.; however, accounts involving allegations of criminal behavior against named individuals or companies MUST be first-hand accounts and may NOT be made anonymously.

If a situation has been reported upon by a reputable news source or addressed by law enforcement or the legal system it is open for discussion, but if an individual wants to make their own claims of criminal behavior against a named party in the course of that discussion, they too must identify themselves by first and last name and the account must be first-person.

Criminal allegations that do not satisfy these requirements, when brought to our attention, may be removed pending satisfaction of these criteria, and we reserve the right to err on the side of caution when making these determinations.

Credible threats of suicide will be reported to the police along with identifying user information at our disposal, in addition to referring the user to suicide helpline resources such as 1-800-SUICIDE or 1-800-273-TALK.

2. Conversations in horse-related forums should be horse-related.
The forums are a wonderful source of information and support for members of the horse community. While it's understandably tempting to share information or search for input on other topics upon which members might have a similar level of knowledge, members must maintain the focus on horses.

3. Keep conversations productive, on topic and civil.
Discussion and disagreement are inevitable and encouraged; personal insults, diatribes and sniping comments are unproductive and unacceptable. Whether a subject is light-hearted or serious, keep posts focused on the current topic and of general interest to other participants of that thread. Utilize the private message feature or personal email where appropriate to address side topics or personal issues not related to the topic at large.

4. No advertising in the discussion forums.
Posts in the discussion forums directly or indirectly advertising horses, jobs, items or services for sale or wanted will be removed at the discretion of the moderators. Use of the private messaging feature or email addresses obtained through users' profiles for unsolicited advertising is not permitted.

Company representatives may participate in discussions and answer questions about their products or services, or suggest their products on recent threads if they fulfill the criteria of a query. False "testimonials" provided by company affiliates posing as general consumers are not appropriate, and self-promotion of sales, ad campaigns, etc. through the discussion forums is not allowed.

Paid advertising is available on our classifieds site and through the purchase of banner ads. The tightly monitored Giveaways forum permits free listings of genuinely free horses and items available or wanted (on a limited basis). Items offered for trade are not allowed.

Advertising Policy Specifics
When in doubt of whether something you want to post constitutes advertising, please contact a moderator privately in advance for further clarification. Refer to the following points for general guidelines:

Horses -- Only general discussion about the buying, leasing, selling and pricing of horses is permitted. If the post contains, or links to, the type of specific information typically found in a sales or wanted ad, and it's related to a horse for sale, regardless of who's selling it, it doesn't belong in the discussion forums.

Stallions -- Board members may ask for suggestions on breeding stallion recommendations. Stallion owners may reply to such queries by suggesting their own stallions, only if their horse fits the specific criteria of the original poster. Excessive promotion of a stallion by its owner or related parties is not permitted and will be addressed at the discretion of the moderators.

Services -- Members may use the forums to ask for general recommendations of trainers, barns, shippers, farriers, etc., and other members may answer those requests by suggesting themselves or their company, if their services fulfill the specific criteria of the original post. Members may not solicit other members for business if it is not in response to a direct, genuine query.

Products -- While members may ask for general opinions and suggestions on equipment, trailers, trucks, etc., they may not list the specific attributes for which they are in the market, as such posts serve as wanted ads.

Event Announcements -- Members may post one notification of an upcoming event that may be of interest to fellow members, if the original poster does not benefit financially from the event. Such threads may not be "bumped" excessively. Premium members may post their own notices in the Event Announcements forum.

Charities/Rescues -- Announcements for charitable or fundraising events can only be made for 501(c)(3) tax-exempt organizations. Special exceptions may be made, at the moderators' discretion and direction, for board-related events or fundraising activities in extraordinary circumstances.

Occasional posts regarding horses available for adoption through IRS-registered horse rescue or placement programs are permitted in the appropriate forums, but these threads may be limited at the discretion of the moderators. Individuals may not advertise or make announcements for horses in need of rescue, placement or adoption unless the horse is available through a recognized rescue or placement agency or government-run entity or the thread fits the criteria for and is located in the Giveaways forum.

5. Do not post copyrighted photographs unless you have purchased that photo and have permission to do so.

6. Respect other members.
As members are often passionate about their beliefs and intentions can easily be misinterpreted in this type of environment, try to explore or resolve the inevitable disagreements that arise in the course of threads calmly and rationally.

If you see a post that you feel violates the rules of the board, please click the �alert� button (exclamation point inside of a triangle) in the bottom left corner of the post, which will alert ONLY the moderators to the post in question. They will then take whatever action, or no action, as deemed appropriate for the situation at their discretion. Do not air grievances regarding other posters or the moderators in the discussion forums.

Please be advised that adding another user to your �Ignore� list via your User Control Panel can be a useful tactic, which blocks posts and private messages by members whose commentary you'd rather avoid reading.

7. We have the right to reproduce statements made in the forums.
The Chronicle of the Horse may copy, quote, link to or otherwise reproduce posts, or portions of posts, in print or online for advertising or editorial purposes, if attributed to their original authors, and by posting in this forum, you hereby grant to The Chronicle of the Horse a perpetual, non-exclusive license under copyright and other rights, to do so.

8. We reserve the right to enforce and amend the rules.
The moderators may delete, edit, move or close any post or thread at any time, or refrain from doing any of the foregoing, in their discretion, and may suspend or revoke a user's membership privileges at any time to maintain adherence to the rules and the general spirit of the forum. These rules may be amended at any time to address the current needs of the board.

Please see our full Terms of Service and Privacy Policy for more information.

Thanks for being a part of the COTH forums!

(Revised 5/9/18)
See more
See less

Melanoma - Oncept - June 2020 - Update post 178

Collapse
X
 
  • Filter
  • Time
  • Show
Clear All
new posts
    Original Poster

    Originally posted by Holly01 View Post

    Good news about the eye melanoma lessening ! Phew ! Thats gotta be good to hear ! Is the Gaskin lump a melanoma ? What are your vets thoughts on Oncept so far ?
    You know, it's been a while since I talked to my vet about it, so I asked her. Will post when I get her opinion.

    I would assume that the gaskin lump is a melanoma, but it has been stable and small and it doesn't interfere with his movement. So, we are just watchful at this point.

    Comment

      Original Poster

      Some comments from Mr Ay-rab's attending vet. She mentions that they have had 15-20 horses try Oncept to date.
      ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ ~~~~~~~~~~~~~~
      From our cases, seems that roughly half of the horses that we've treated have had some sort of a positive response to the vaccine (a couple of dramatic ones, like Monty [aka Mr Ay-rab], in which the lesions essentially went away after a couple of months on protocol) - there have been relatively few adverse effects, and among those, they were almost all minor (local swelling that went away within 24 hours), so it seems to be well-tolerated in horses.

      What we are often asked about but have absolutely *no* idea how to accurately answer is whether this vaccine can be used prophylactically, say, started early in young grey horses to prevent melanoma later in life. To my knowledge, there are no data reported on this type of use - given early enough, might very well give them vitiligo, who knows (which, incidentally, a colleague reported as an adverse effect in one of her treated patients)!

      On the whole, our experiences with this product have been positive, with the worst outcome, really, being that it doesn't seem effective at all in some horses - AND, we have no good way to identify those non-responders before spending quite a bit of money testing the waters, so to speak... Biggest downside that we've identified so far = expense (!)
      ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ ~~~~~~~~~~~~~~~
      So there you have it, straight from the source! Happy Holidays!!!

      Comment


        Thank you!
        Nothing with horses is ever easy or cheap. And if it is, you're doing it wrong. They always rip out part of your soul when they leave. I guess that's how they find us later.

        Comment


          Thank you for the updates.
          GO TARHEELS!
          COMH
          http://community.webshots.com/user/funnyknuckles
          http://community.webshots.com/user/funnyknuckles2

          Comment

            Original Poster

            Wow! Just noticed that this thread is now over 18,000 views! I hope it's been helpful! Best of luck to all my fellow gray horse owning posse!

            Comment

              Original Poster

              So after 5 years of sailing through appointments at OSU, it's been a wild ride for the last month.

              Had the vet out for the spring dental and sheath cleaning appointment. When Mr Ay-rab dropped his penis after a little happy juice, vet noticed lumps that none of us had seen before, certainly not at his last sheath cleaning a year ago. Took pictures, sent to OSU, and new melanomas were suspected.

              He had laser surgery Friday to remove the lumps on his penis and they were definitely melanomas. I also had them remove the hard lump on his gaskin that didn't seem to be a melanoma. They found two others like it on his stomach and lasered those. I am waiting for the pathology report for these.

              He got another Oncept injection while he was in recovery.

              He spent a couple days at OSU recovering and came home today. No apparent ill effects - he came off the trailer in fine shape and seemed to be happy to be home. He has to spend time on stall rest until the sutures come out on his gaskin. So it will be a while before he resumes his role as king of the yearlings.

              Here's the really puzzling thing - nothing has happened at all in his old sites. His eye looks good, the very small lumps internal to his jugular groove are hardly noticeable, and the lumps under his tail remain very small. I really don't know what to make of this. I don't think we know enough to know what to make of it!

              So we will forge on. Seems like his purpose in life is to be a science experiment, so we will see where this takes us.

              I am sure someone will ask the logical question, which is am I sorry I started him on Oncept? Has it been a waste of money? My answer to both is absolutely not. I am pretty darn sure he wouldn't be with us at all at this point without Oncept. He's earned the right to have some money spent on his health since he has been exceptionally low maintenance in every other way.

              Will keep you posted when I get the pathology report.

              I don't think there's an emoji for what I feel right now - kind of a cross between WTF, horses, and relief that he is OK.

              Comment


                Wow, how interesting.

                Any chance there are tissue samples from his original tumors? DNA analysis of those versus the new ones would be really intriguing. Not that you'd want to pay for that, but a vet on his team could perhaps get a paper out of it, along with the potential for some really nice data about equine melanoma!

                Fingers crossed that this is a brief blip and nothing more than a curious footnote! Thank you again for sharing your journey here.

                ?????

                Comment


                  Thanks for the update. Very interesting.

                  Last fall my mare has had three small lumps under her tail. She had one removed when she was just 2 y.o. She is now 17 so development is certainly not unexpected. When I checked her recently, I was dismayed to find at least 10 small but palpable lumps...bummer. My current 'maintenance' vet (who is nearing retirement) of course says there is nothing you can do about them. We can tell who hasn't been keeping up. I am currently grounded for around 3 months due to foot surgery but will take her later this summer or early fall to our local referral hospital to see if they offer Oncept or at least get an idea when to get them de-bulked. I won't let her tail become a big mass of tumors. Yes, there is something that can be done.

                  Susan

                  Comment

                    Original Poster

                    Today's minor update: the lump on his gaskin, and two like it on his stomach, are not melanomas. However, vet called to ask to do more pathology tests because they are not sure what they are. Stay tuned.

                    Only my horse

                    ETA: He also had a gas colic attack yesterday, poor guy. He's doing fine today. For a horse that *rarely* sees a vet outside of his Oncept injections, he's had quite the week!

                    Comment

                      Original Poster

                      So I got the pathology report today for the extra tests on the lump from his gaskin. The lump was a mast cell tumor, which the lit says is rare in horses. So of course we have it! My horse, the walking dermatology textbook! Excision is the cure, which is done now of course, and the margins were clear. So, only task now it to just keep an eye on his body for new growths.

                      He returned to his job of ruling the yearlings on Monday and seems to be just fine.

                      It certainly has been an experience with him!

                      Comment


                        Originally posted by oldernewbie View Post
                        So I got the pathology report today for the extra tests on the lump from his gaskin. The lump was a mast cell tumor, which the lit says is rare in horses. So of course we have it! My horse, the walking dermatology textbook! Excision is the cure, which is done now of course, and the margins were clear. So, only task now it to just keep an eye on his body for new growths.

                        He returned to his job of ruling the yearlings on Monday and seems to be just fine.

                        It certainly has been an experience with him!
                        Wow! It must at least feel good to know what the lump is and know that it is taken care of.

                        Thank you for sharing your journey's ups, downs and insights.
                        "So relax! Let's have some fun out here! This game's fun, OK? Fun goddamnit." Crash Davis; Bull Durham

                        Comment


                          Oh my gosh what a rollercoaster ride. Interesting how the Mast cell tumour is not targeted by the Oncept, only very specific to melanoma. It is like a science experiment alright !

                          Comment

                            Original Poster

                            It was off to OSU this morning for Mr Ay-rab's semi-annual Oncept injection. I was very happy with the results - no new mast cell tumors, old melanomas stable to pretty stable, no re-growth of melanomas on his penis. Perhaps the only area of concern is his eye as it seems to look different both to me and to Dr Burns, but not radically so. I think another trip to his ophthalmologist is in his future, but probably not until early spring unless something really goes haywire. I am not a fan of driving in the snow with a horse trailer.

                            He got his exam, injection, treats, hopped back on the trailer, and ruined a perfectly good grooming job when he got home by rolling on both sides in the muddiest part of the field. Life is good!

                            Comment


                              Hello. I have a 16 yr old grey Arab with a few melanomas in his sheath. I am serious about the oncept vaccine but have had trouble locating a vet that can do it. I have been quoted several thousand dollars for the injections, plus a office visit. Of course I am willing to do this but also would like to save some money if I can. does anyone have any suggestions? I am in Norco and my main vet cannot get the vaccine as he is not a oncologist nor a internist. Please help. Thanks, Robin

                              Comment

                                Original Poster

                                Originally posted by horselovrrn View Post
                                Hello. I have a 16 yr old grey Arab with a few melanomas in his sheath. I am serious about the oncept vaccine but have had trouble locating a vet that can do it. I have been quoted several thousand dollars for the injections, plus a office visit. Of course I am willing to do this but also would like to save some money if I can. does anyone have any suggestions? I am in Norco and my main vet cannot get the vaccine as he is not a oncologist nor a internist. Please help. Thanks, Robin
                                horselovrrn

                                You know, around here (Ohio), Merial is letting regular horse vets without any special credentials buy and administer Oncept. All they have to do is buy the intradermal injector. This is a change from their earlier policies which did require a diplomate in oncology or internal medicine. It is nutty to me that they have apparently different policies in different parts of the country? I think I would have your vet run this up the chain of command (so to speak) at Merial and see if he/she can get a read that is more consistent with other parts of the country. Second choice is to try a vet school and see if they can help.

                                Good luck and let us know how it goes.

                                Comment


                                  Hi. thank you! I did try Western University out here and left them a message. I hope they get back to me soon. If I was NOT in California things would be so much easier for sure.Or, the UK where they do it all the time.

                                  Comment

                                    Original Poster

                                    Originally posted by horselovrrn View Post
                                    Hi. thank you! I did try Western University out here and left them a message. I hope they get back to me soon. If I was NOT in California things would be so much easier for sure.Or, the UK where they do it all the time.
                                    Be persistent. Not everyone knows about Oncept, and even if they do know about it, aren't too motivated to start using it unless a client insists. Good luck!

                                    Comment

                                      Original Poster

                                      It was time for Mr. Ay-rab's 6 month Oncept injection - quite a different trip in the COVID-19 era! You pull in, call a phone number, the tech and intern come out and get the horse. Wait a few minutes, and the tech and intern bring back a horse with a new injection. No gaggle of vet students to take a look at Mr. A's eye, no gossip with vet. I really miss that!

                                      The good news is - he's doing fine. No big changes. No adverse reaction to the injection. Took him home and we're both happy!

                                      Stay safe everyone!

                                      Comment

                                      Working...
                                      X