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Horse developed seizure-like reaction to IV & IM banamine???

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  • Horse developed seizure-like reaction to IV & IM banamine???

    I am really curious to see if anyone has had a similar experience... my gelding is at NC State being treated for bacterial pneumonia. He was on banamine at home; prior to being transferred to State, and the last IM shot I administered resulted in a bizarre reaction- laid down within minute, went into a coughing fit followed by obvious respiratory distress, and even had a few seizure-like twitches. This was all relayed to the vets at State, but 24 hours later they gave him IV banamine, and the same thing happened, a little worse even.

    This horse has never had a problem with banamine...even the vet said it was "bizarre" - but didn't offer much explanation beyond that. Has anyone ever run into a sudden allergy like this, when they have been fine before???

  • #2
    I've seen a reaction to lidocaine in an IM antibiotic before. The horse didn't react the same as what you describe, but I thought she was going to crawl out of her skin. It was over in 5 minutes and was confirmed by the vet to be a lidocaine reaction.

    Is your horse okay now? Why were they giving him IM banamine?


    • Original Poster

      My boy is doing MUCH better now. I was the one doing the IM- ran out of paste and I am still not super comfortable giving IV. The vet was doing IV though; and he had the same reaction. So strange- he had been on it for three days already without any adverse reaction. The vet still doesn't really have an explanation...


      • #4
        If you are not comfortable giving the injectable form IV, give it orally. Works just as, if not faster, than if you give it IM and there is no risk of clostridial myositis. Just for future reference.
        Only two emotions belong in the saddle: One is a sense of humor. The other is patience.


        • #5
          I'm glad he's doing better. Do a google search on giving banamine IM, or clostridial myositis. This was new to me until recently and I have given it several times IM, but will never do it again!


          • #6
            While I do love banamine, if your horse is reacting to it regardless of route of administration, don't give it to him.
            McDowell Racing Stables

            Home Away From Home


            • #7
              Yess! This happened to my guy recently when he was given IV banamine for gas colic! Scared the life out of me. Never. Again. EVER
              ~Run and Jump!~


              • Original Poster

                Xcjumper- had you ever given it to him before? The bizarre part was the out-of-the-blue reaction, when he has had it plenty of times in the past??!!

                As for the IM/oral issue; I just found out about the risks this week - definitely plan to make some changes in the future!!!


                • #9
                  He had not gotten any Banamine before that I know of unless he got some at the track 3 years ago...But he definitely had seizure like activity and his eyes rolled back in his head, tremors all over. My friend kicked him in the head and he woke up, jumped up and started eating the grass....totally weird!
                  ~Run and Jump!~


                  • #10
                    Regardless of the advisability of using Banamine IM, which is not worth rehashing here, if a horse had a weird adverse reaction TWICE to using a drug, I'd quit using it unless some really, really plausible explanation taking the drug off the hook came to light.
                    Click here before you buy.


                    • #11
                      Originally posted by deltawave View Post
                      Regardless of the advisability of using Banamine IM, which is not worth rehashing here, if a horse had a weird adverse reaction TWICE to using a drug, I'd quit using it unless some really, really plausible explanation taking the drug off the hook came to light.
                      What delta said.

                      Query to the OP--was the horse running a fever at the time of the reactions?
                      "It's like a Russian nesting doll of train wrecks."--CaitlinandTheBay

                      ...just settin' on the Group W bench.


                      • Original Poster

                        Delta; it was discontinued. The vets initially did not blame the banamine as the initial cause since he was still undiagnosed; and it would have been so bizarre to have suddenly developed a reaction. Believe me; this horse will never again be administered banamine!!!

                        Ghazzu, yes- he was in the 102-103 range both times. He had been up to 105 in the past 2 days when it was given.


                        • #13

                          My WB had a similar reaction yrs ago, his temp was running between 103 and 104. When the IM banamine was given his temp dropped like a rock (to fast) and affected his breathing in a very scary way! He was heaving in order to breathe!! He will never be given banamine in any way again!! Glad your guy is good now!!!