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something to kill adult Onchocerca? 19 CASE STUDIES POSTED-PAGE 58

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  • My mare had something like that...

    Originally posted by short strided View Post
    I double dosed one of my guys two weeks ago and will do it again tomorrow. The itching is better, but not totally gone. He has not rubbed off anymore hair and the bald spots are filling in.

    This is the really gross part... He has had a horny growth on his back right fetlock since I bought him (about 5 months ago). I really thought it was scar tissue from an old injury, as I had tried to peel it off with no success. Well... two days after the double dose the thing completely peeled off to reveal relatively normal skin with a very small wound in the middle. Coincidence? Perhaps... Something living in there? Perhaps.
    ===========
    Short Strided - how wierd! I dunno if it's the same thing, but my mare had some growth like that on her hock area, but I thought it was related to an oldish wound. Like some wierd scar/proud flesh thing. But I "took it off" - it was a perfectly round circle, sort of just raw in the very center...

    Do you know what it was on your boy? That growth thing? Ewwwwww . This whole thread gives me the eebie jeebies!
    ~~~~~~~~~~~~~~~~~~~~~~~
    Equine & Pet Portrait Artist
    www.elainehickman.com
    **Morgans Do It All**

    Comment


    • Originally posted by ChocoMare View Post
      Anyone else ready to report in on their horse's condition?

      Would also like to keep this on Page 1 to keep educating the masses
      ChocoMare,
      I did my final double dose last Thursday.. I'd like to report her condition, but how long will it take before I see results?

      Would it be a good idea to give her a nice "scrubby" bath?
      MnToBe Twinkle Star: "Twinkie"
      http://i236.photobucket.com/albums/f...wo/009_17A.jpg

      Proud member of the "Don't rush to kill wildlife" clique!

      Comment


      • For those who also observed welts post-treatment:
        http://www3.interscience.wiley.com/j...TRY=1&SRETRY=0

        Apparently this is not uncommon. The article cited above states that weals were noted 4 to 24 hours after treatment and regressed after about a week.

        The vet is coming out Friday to check the welts (hopefully they'll be gone or mostly gone by then!) but he didn't think this was likely caused by threadworms. In my uneducated opinion though, the welts this close to the treatment more confirms my suspicions that he was infected. At any rate, I will be doing the 2nd double dose of equimax in 2 weeks to be sure.

        Comment


        • Just as Meaty just posted, if it was, indeed, NTWs you should have seen results within 24-48 hours of the first dosage.... new bumps as the dead microfilia emerge/leave the body.

          Now, if there was no real load of NTWs, you might not see much of anything.

          A nice bath with Nolvasan Surgical Scrub to get any lasting microbes is never a bad thing. Just let the foam sit for about 10 minutes so it can do its job.
          <>< Sorrow Looks Back. Worry Looks Around. Faith Looks Up! -- Being negative only makes a difficult journey more difficult. You may be given a cactus, but you don't have to sit on it.

          Comment


          • Originally posted by ChocoMare View Post
            Just as Meaty just posted, if it was, indeed, NTWs you should have seen results within 24-48 hours of the first dosage.... new bumps as the dead microfilia emerge/leave the body.

            Now, if there was no real load of NTWs, you might not see much of anything.

            A nice bath with Nolvasan Surgical Scrub to get any lasting microbes is never a bad thing. Just let the foam sit for about 10 minutes so it can do its job.
            I hope this is the case! I really think so, as there was nothing else it could have been. He is still looking great on his muzzle/forelegs, which has never happened before as those were the places I could not keep covered up. I have his hood and sheet on again because he is itching so badly, just to keep him from tearing himself up too much. I find it interesting that it was the second dose in our case that I really have seen something. For everyone who has just done the first dose, make sure and do the second. It maymake a big difference!

            Comment


            • A horse where I work has what the vet said was sweet itch. He treated him by a coritsone shot and some topical ointment. That did nothing. He has sores along his mane, tail, chest, and sheath. He will almost take the barn down trying to rub his tail. I know that he was on a regular worming program.
              Well, I told the owner about double dosing w/the Equimax. She did it yesterday. Is it possible that it is actually working w/in 24 hrs? He did not rub or itch the whole time I was there this morning, which is pretty amazing!
              http://www.chronicleofmyhorse.com/profile/Jen75

              Comment


              • Damn horse is rubbing her tail still. I cleaned her teats as well.
                Missouri Fox Trotters-To ride one is to own one

                Standardbreds, so much more then a harness racing horse.

                Comment


                • Originally posted by Cashela View Post
                  Damn horse is rubbing her tail still. I cleaned her teats as well.
                  From what I'm reading here, the itching gets worse before it gets better. Some have indicated that it's about 3 days before they see an increase in itching.

                  Hang in there....

                  Comment


                  • ChocoMare ... can you do a summary?

                    Can someone do a summary of: Symptoms, treatment, Results typically seen.

                    And then perhaps update the title of the thread (with the OPs permission)...

                    We don't want to lose all the other anecdotal info or the links that so many have posted.

                    Comment


                    • Originally posted by gabz View Post
                      From what I'm reading here, the itching gets worse before it gets better. Some have indicated that it's about 3 days before they see an increase in itching.

                      Hang in there....
                      Day four for my horse--she rubbed the crap out of her tail yesterday and was double dosed on Thursday. Very sad to see even MORE tail hair coming out

                      Comment


                      • When I got off work last night I checked my boy in his pasture and though the welts near his croup had gone down, his neck and jowls were covered with very narrow, linear welts, looking almost like raised veins on an overexerted horse, though not connected as such, and longer. If it's not a die-off of onchocerca cervalis I don't know what it is. It's got to be. He was extraordinarily itchy and stood hanging his head so I could scratch. Thankfully those were down by this morning as well. I'm wondering if the round welts nearer his croup were some other species or onchocerca as well? Vet still says neck threadworms are unlikely but I'm convinced otherwise and only a negative skin biopsy would unconvince me at this point.

                        For those comparing timelines, I dosed mine Friday PM, initial welting appeared Sunday PM with neck welts arriving Monday PM. So 48 hours and 72 hours respectively on the hind and neck welts.

                        The two other horses that I dosed were both negative for welts and continue to be, so I'm thinking no threadworms there and probably will not complete the 2nd double dose of Equimax on them.

                        Comment


                        • Read the whole thread - and have ordered the EquiMax for my mare! She seems to have fly/gnat allergies - but, some of her symptoms sure match what I've read here. She is not nearly as itchy as some of the horses mentioned - but she has lost a lot of hair on her face recently and gets welts that turn into small bald patches once the swelling goes down . . . It sure can't hurt to try the EquiMax.
                          http://fromdressagehorsetocowpony.blogspot.com/

                          "I am still under the impression that there is nothing alive quite so beautiful as a thoroughbred horse." -- John Galsworthy

                          Comment


                          • OK, after reading the thread, most of the linked articles, more articles I found after googling "onchocerca equine" and a few other combinations....

                            I ordered the Equimax and double dosed my herd on the 21st.

                            I then gave everyone 10mg of Dex powder in the morning feed the next day based on one of the other studies I had read. I figured it would also help with the hideous itchies that come along the next day.

                            So far, the one whose tail I was OCD about seems to have stopped rubbing. The hard lump she's had all summer on her shoulder, is shrinking.

                            I'll follow up w/ a double dose ivermectin on Sept 4.

                            Comment


                            • Since I'm convinced that one of my horses has an adult neck threadworm infestation, I've also been doing a lot of research, and I kind of wish I had done that prior to doing the double Equimax.

                              It seems that nothing has been proven effective vs. the adult onchocerca, and studies have shown that moxidectin (Quest) is more effective agains the microfiliae than ivermectin, and also results in lesser incidence of the related dermatitis. I have dewormed this horse with Quest previously, but honestly, I am probably overcautions with Quest due to the reported issues and toxicity and I wonder if I underdosed him as a result. Actually I'm fairly certain that I did underdose him as the max dose on a full tube is 1150lbs, less than his wieght by over 200lbs. D'oh. Smacking head now.

                              http://www.ncbi.nlm.nih.gov/pubmed/8915126
                              http://www.jstor.org/pss/3284021
                              (these articles refer to the superiorority of moxidectin over ivermectin against the onchocerca mf. and the lack of dermatits in moxidectin-treated equines respectively).

                              FWIW, there are human studies right now regarding moxidectin efficacy against the onchocerca volvulus. I'll be very interested in those results. http://www.druglib.com/trial/68/NCT00300768.html

                              Comment


                              • Very interesting thread, I just read all of it! Thanks to you guys that have done all the research.

                                So now, I have some questions, oh queens of worming and itchy horses

                                The Red Mare has been on a regular rotational deworming program for her entire life (she's 14 now). I was planning on doing a Power Pac in October after the first freeze. She has not been Power Pac'd before. She has a few of the symptoms of these neckworms, like a slightly itchy tail, a few bumps on her chest and back legs. Nothing really dramatic, though. She hasn't been wormed for a month or so, so what would be your recommendations? A double dose of Equimax in September two weeks apart and then can I still Power Pac her in October? Or would you split that up? Wait until November for the Power Pac (first freeze here is usually mid to late Oct)? Next spring?

                                EqT, if you don't mind my asking, what is your deworming rotation?

                                Caitlin
                                Caitlin
                                *OMGiH I Loff my Mare* and *My Saddlebred Can Do Anything Your Horse Can Do*
                                http://community.webshots.com/user/redmare01

                                Comment


                                • Originally posted by RedMare01 View Post
                                  ... A double dose of Equimax in September two weeks apart and then can I still Power Pac her in October?
                                  Yup.
                                  <>< Sorrow Looks Back. Worry Looks Around. Faith Looks Up! -- Being negative only makes a difficult journey more difficult. You may be given a cactus, but you don't have to sit on it.

                                  Comment


                                  • May be on to something...

                                    We have a teenage thoroughbred mare in the barn that has had a skin problem for as long as the owner can remember. It became really, really bad this past spring/early summer. Owner/Vet convinced it was just a really bad case of rain rot- tried all sorts of meds/creams/etc... She basically became bald on the face, neck, shoulders, back and rump area. Blood tests revealed nothing. Mare also has bad swelling in the hind legs, pastern area. After reading post after post and doing my own research- we decided to worm everyone in the barn w/ a double dose of Zimectrin gold as we were unable to find the Equimax locally and compairing ingredients, Zimectrin has the same ingredients just a lower dosage. Anyways- it's been a week since she was wormed w/ everyone else and low and behold, her face/body is actually 50% better than it was a week ago, legs not as swollen. She's not itchy and her back is no longer oozing/flakey and no more welts. I'm convinced and will follow up the the 2nd dose next week! Morning before worming she was covered with what looked like little bites/hives all over her chest, neck and belly area, nothing since being wormed. Mare is visibly more comfortable and happier. Keeping my fingers crossed..

                                    Comment


                                    • Originally posted by Fancy That View Post
                                      ===========
                                      Short Strided - how wierd! I dunno if it's the same thing, but my mare had some growth like that on her hock area, but I thought it was related to an oldish wound. Like some wierd scar/proud flesh thing. But I "took it off" - it was a perfectly round circle, sort of just raw in the very center...

                                      Do you know what it was on your boy? That growth thing? Ewwwwww . This whole thread gives me the eebie jeebies!
                                      Fancy That- I have no idea what it was/is. I am keeping a close eye on it and his other fetlocks as well. He now has hairless spots on both fronts.

                                      Comment


                                      • I wormed my 3 girls last night with plain ole Ivermectin 1.87%, single dose. The box says that a normal dose DOES kill neck thread worms. So...why do you have to do the double dose? They can't just stick that on the box unless it's true, can they?

                                        I always give them the whole tube even though Sweets and Libbey are around 900 and 950 lbs each. They're all VERY good about taking wormer and never lose a drop, so I know they get the full 1250 pounds worth.

                                        But after reading the box I was just confused about the double dose thing and couldn't force myself to do it.

                                        I also bought 3 boxes of Tape Care Plus because I always do a tapeworm wormer in the fall. I'll wait 2 months and then do that one.

                                        Comment


                                        • Originally posted by Cashela View Post
                                          If I was A2 I would definitely start with something mild like a dose of ivermectin. That is what I was told to do by my vet when I rescued a horse once and hadn't know when he had been wormed last.
                                          Thanks everyone for the thoughts about Libbey! I gave her a dost of Ivermectin a year ago and haven't done anything since. So last night I gave her a full tube of Ivermectin and this morning she looked fine. I'm still worried but if she stays fine over the next couple days, I will give her the TApe Care Plus dose in 2 months. I might be convinced to do a double dose of something but I swear I stood in the farm aisle last night for 20 minutes trying to convince myself and I couldn't. LOL! I promise I'm not hopless, just really scared of chemicals.

                                          Comment

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