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Success treating old Lyme infection?

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    Success treating old Lyme infection?

    I've had my OTTB for 3 years. The first year she was just about perfect, as far as horses go. Then she had a sudden change of behavior followed by some intermittent movement abnormalities (can't really call them lamenesses; just not quite right), occasional explosions under saddle (usually related to extremely exaggerated spooking or tripping/slipping), and hyperesthesia. Most of this is intermittent, but the hyperesthesia seems to be sticking around at this point. Lately as we have begun to work more with the spring weather, she has gotten somewhat lethargic and depressed. Over the last 2 years, I've had saddles fitted, checked hormones, x-rayed for kissing spine...we have come up empty everywhere. I've suspected Lyme for about 6 months, but my vet has not been keen on testing. I've gotten her on board and will be doing the Cornell Lyme test in the next couple of weeks and then treating accordingly. Does anyone have any (hopefully) success stories of treating long-untreated Lyme infection? If positive, I'm leaning towards doing the IV oxytet and then oral minocycline (I believe that's what I've read is the most effective current treatment). Likewise, if you have had any bad experiences treating a horse like this, I guess I should hear those too. Thanks in advance

    #2
    Be prepared to treat with a fairly lengthy course...like 60 or more days of the Minocycline after the Oxytet. My horse's treatment for acute Lyme was 60 days doxy, with probiotics and ulcer meds throughout (ouch $$). I've had a few clients whose horses have chronic Lyme, it can be a long road and some of them went through 2 or more rounds of doxy/minocycline. (At least one of them tried 30 days first and it only partially cleared it, so did the Oxytet plus 60 or 90 days doxy.) Best to hit it hard.

    The symptoms you describe would have had vets here (in Lyme central) pulling a titer right away, so you may need to do some convincing to get your vet to do such a long treatment protocol if she's not familiar with treating it. One of the horses who was hyper-sensitive did well with supplemented Magnesium and Vitamin E in addition to the ABx.

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      Original Poster

      #3
      Thanks Dutchmare. Interesting about the Mag/Vit E. That might benefit her even before starting ABx. I'm fairly competent at giving IV injections, but I don't want to ruin a vein. Is it feasible for an owner to give BID IV injections for a week or so? She is easy to give injections to. Approximately how much oxytet is given per injection? The mare is on 24 hour turnout with run-in sheds so I don't really want to stall her, if possible. And the vet is also a horse rescue so constantly has horses coming in and out and I'd like to avoid sending her there. Thanks again for your thoughts. It's very helpful.

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        #4
        They will (probably) put a catheter in for the Oxytet, I had it for anaplasmosis a few years ago and I added the oxytet to a liter of saline and let it run in that way.

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          Original Poster

          #5
          Ahh, that makes sense. Thanks so much!

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