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  1. #1
    Join Date
    May. 17, 2010
    Posts
    331

    Default Protocol for using both Adequan and Legend

    Hello COTHers:

    My horse came up with a stifle issue in Nov. Big name vet recommended Legend IV x3/ once a week. Local vet says she often uses them in conjunction. Adequan subQ every 2-3 days, followed by 1 injection of Legend. Then drop the Legend and continue with Adequan.

    I read on a recent thread that the current reccomendation for Adequan is loading dose, off for 6 mos. Repeat loading dose, no proven effect for continuing Adequan.

    Who uses both, what is your protocol, and what do the studies say?

    No pentosan.

    TIA,
    PKN



  2. #2
    Join Date
    Jul. 24, 2008
    Posts
    120

    Default

    I have elderly horses with various injuries/arthritis. I use Legend 1x/month and Adequan 1x/week. You could probably do the loading dose of Adequan, then use it and Legend once/month.

    Granted, mine are extreme cases, but I've always had better luck with continuous use of Adequan, rather than stop and restart.



  3. #3
    Join Date
    Mar. 8, 2004
    Location
    Baltimore, MD
    Posts
    15,113

    Default

    I don't use either anymore because I like Pentosan better but when I did use it I would give the loading dose of Adequan ie every four days for 7 doses then give Legend 24 hours out before the race.



  4. #4
    Join Date
    May. 17, 2010
    Posts
    331

    Default anyone else?

    No one else uses these drugs in combination?



  5. #5
    Join Date
    May. 4, 2011
    Posts
    76

    Default

    The only Adequan protocol that was researched and found to have had disease-modifying effects is the 1 vial every 7 days for 28 days protocol. Other dosing schedules that people have come up with have no proven benefit.
    I can't comment on Legend dosing, as I've never seen them used in combination.



  6. #6
    Join Date
    Apr. 13, 2001
    Location
    Fort Collins, CO
    Posts
    14,869

    Default

    When I used both, I used them each once a month. I cannot recall if I gave both on the first or if I gave one on the first and one on the 15th....it has been several years.

    I eventually retired the horse because we just could not keep her sound.



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