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  1. #1
    Join Date
    Feb. 3, 2012
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    100

    Default Doxycycline - long term use, any side effects?

    Anyone's horse been on doxycycline for longer than 3 months? Are there any side effects/risks from using Karidox solution/doxycycline for a long time (such as 6 months)? Thanks for any replies.



  2. #2
    Join Date
    Feb. 1, 2008
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    Nowhere, Maryland
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    3,114

    Default

    It can be pretty tough on horses' stomachs. We had a foal with joint ill/ bone infection who got it for several months and the vet eventually had us give her breaks from it-- I think she was on it for five days off for three? Something like that, anyway. She never showed any ill effects from it.


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  3. #3
    Join Date
    Aug. 22, 2009
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    1,007

    Default

    Not too bad long term in humans - teens use it for acne for years at a time and do ok. Taking with food/feed will minimize some of the GI upset though it shouldn't be taken with vitamin supplements.

    The worst I've seen is some serious 2nd degree sunburn for people on it if sunblock isn't used. Also most drugs when they "get old" don't really become harmful - just less effective. Doxycycline is actually harmful once it's expired, so make sure you have non-expired product.


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  4. #4
    Join Date
    Feb. 14, 2008
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    924

    Default

    My horse was on it for close to a year. Towards the end of his treatment he did develop ulcers, but just added in Ulcer guard and he was fine.


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  5. #5
    Join Date
    Feb. 3, 2012
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    100

    Default

    SuperD what did your horse start doing for you to suspect ulcers while on doxycycline if you don't mind me asking?



  6. #6
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    Jul. 18, 2004
    Location
    Red Bank, NJ
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    1,647

    Default

    A horse at my barn was on it (twice) for Lyme, and it seemed to affect the texture and color of her coat (sort of dry and more bleached/patchy than usual).
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  7. #7
    Join Date
    Feb. 3, 2012
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    100

    Default

    Quote Originally Posted by Alibhai's Alibar View Post
    A horse at my barn was on it (twice) for Lyme, and it seemed to affect the texture and color of her coat (sort of dry and more bleached/patchy than usual).
    Thats interesting, my filly had doxy April/May last year, her coat went like skin, like she was clipped. When she finished the doxy she grew a thick coat in June, while wearing a rug. Went back on doxy in July and now in the middle of winter again has a really thin coat that looks like its clipped. She is rugged so possibly it would be different if she wasn't rugged. I've been wondering if it was due to the doxy.



  8. #8
    Join Date
    Jan. 16, 2002
    Location
    West Coast of Michigan
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    36,321

    Default

    In addition to the other things mentioned, antibiotic resistance and antibiotic-associated colitis and killing of "beneficial" bacteria are possibilities as well.
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  9. #9
    Join Date
    Jan. 5, 2009
    Location
    Central, FL
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    848

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    She is most likely getting sunburnt. Doxy makes you extremely vulnerable to the sun.

    Doxy is also going on back order and the price will be shooting through the roof very soon.
    --Luck is what happens when preparedness meets opportunity--



  10. #10
    Join Date
    Feb. 3, 2012
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    100

    Default

    Quote Originally Posted by Justmyluck View Post
    She is most likely getting sunburnt. Doxy makes you extremely vulnerable to the sun.

    Doxy is also going on back order and the price will be shooting through the roof very soon.
    I'm in the UK, not much sun at this time of year so no danger of sunburn!

    I feed her prebiotics twice a day, at least 4 hours before or after the doxy so hopefully they are doing something good before getting killed off by the doxy.



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