Yes. It required heavy duty antibiotics which in turn required a lot of stomach protection (we fed the antibiotics in a fruit salad of fresh papaya, applesauce and aloe juice). At one point, he was getting 140 pills a day as we were treating the uveitis with steroids as well. Unfortunately, it was diagnosed late and my horse ended up losing his sight. He did well with the treatment otherwise and is quite healthy today.
Yikes! My dog had leptosporisis 3 years ago, before they really started vaccinating for it. She had to go on some antibiotics and recovered fairly quickly. Now, I get them the vaccination for it regularly and no more bouts of lepto.
I didn't realize that horses could get it! Well probably so since it's in animal urine and they eat grass and are around pooling water areas that could have urine in them. I guess it would make sense too that it could be more serious for them because they can't vomit to rid their bodies of the bad stuff like dogs can. I wonder if they can vaccinate horses for it too now?
My broodmare had it. The only sign she showed was blindness. There were a couple other mares in that same pasture that went blind as well. Her daughter aborted at 273 days due to suspect lepto exposure. Thankfully she had no other effects from it.
The vaccine that can be used for horses is manufactured for cattle. From my vet, she strongly recommends against it unless the situation is dire (ie: young horses in an endemic area). Apparently, there are some nasty side effects and it's no guarantee.