no..and I have used it or freedom 45 religiously every two weeks in fly season for years...on everything from the 31 yo donkey to the Tbs and the CObs and ponies...and I use Wipe daily for faces and belly line ticks
Mine also fuss when I apply it, and have a few welts for a day. But it's the only product I've tried that really works for ticks (which are bad this year), so I have continued using it (haven't found one on my horses since starting the EquiSpot). It does seem to help with flies also. I feel the benefits outweigh the initial discomfort, especially for my pasture-kept horse. I have used the Freedom 45 spot-on, which didn't cause any reactions, but did not find it effective.
We did our barn (15 horses) and one had a reaction. I think it's horse specific- as in some horses react and some don't. I also did notice the new packaging this year and wonder if they changed the formula at all- it seemed to smell more orangy this year- less citronella.
I have used Equi-Spot for several years on a couple of different horses and have never had a reaction.
Even the big green headed horseflys will land but take off right away and the gnats and ticks have packed up and moved elsewhere. I love Equi-Spot and can ride anytime of the day or night without being bothered by flys, gnats, ticks, or mosquitos.
1 reaction out of many horses/applications - interestingly, her 1/2 sister is fine
I use it on all my horses, other than the girl who reacted (welts, itching) Is really the only thing that really helps with the B-52s and, especially, ticks. My chestnut mare would probably go insane without it - she gets welts all over from the bugs and will run herself silly, if I can't get rid of the bugs.
We DID get guinea fowl this year - so might not need it!! (better be worth all that screaming!!)
Since we humans can be allergic to pyrethrum I don't see why horses can't be either. It's a very common summertime allergen for us especially if we use flyspray when our skin pores are open on a very hot day. So the spot-ons are very concentrated. Try making sure you don't apply to your horse to any sweaty areas (pores open) or during a hot time of day. This is true for flyspray too. And try only on the hair-not the skin. I find mine stop fussing after about 10 mins and no harm is done. My dog & cats do this too btw. The pay off is worth the price to me!
Mine certainly weren't overly clean. They live out in the pasture and pretty much only get bathed before a show, and none of them were competing that year (one was too young, another has been retired for some time, the third is not a show horse).
It might have been the temperature, though. As I recall I did apply it at midday on a pretty warm day. They weren't obviously sweaty that I can recall but they may have been beginning to.
Regardless I live in the desert now so not enough bugs to warrant it.
I used the new packaging for the first time yesterday. I first hosed off my horse with just water because he was very sweaty. I put it on and didn't notice any reaction at all other than his usual dislike of having anything put on him. There is definitely a different smell with the new packaging. I have never had a horse have a reaction with the old packaging either. Checked on him today and there was no reaction to it so I guess it just depends on the horse.