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Pookah
Mar. 12, 2010, 10:03 AM
Hoping that all of the combined knowledge on COTH might be able to help out with some horsey weirdness.

The horse in question is a 19 year old Hanoverian gelding, has been with current owner for 3 years. He's a big guy, about 17.1, has always been super healthy and hardy--prefers to be out as much as possible, very laidback and easygoing. He is in a very quiet semi-retirement barn, where he is one of four pretty aged horses. They are turned out together daily (nighttime in the summer) in a 5 acre field, and come in at night to stalls with attached paddocks. It's very low-key and quiet.

This winter, Steiny got very little work because of our terrible weather, plus a back injury for his owner (he is typically a lower level dressage horse, in light to medium work). His grain, supplements, and hay have not changed (except to increase his grain in recent weeks), but we have noticed in the past 6 weeks that he has lost weight, muscling, and bloom over the winter. The loss of muscle is very generalized and equal on both sides--just looks like he has not been in work and has slightly less muscle, although not severe. It is, however, more muscle than he has lost in the past when out of work.

In November, he began having odd episodes when he came into the barn for evening feeding. On the days when he has these episodes, he comes in very anxious--wild-eyed, almost charging into the barn, jigging, clearly very "up." He is not terrible, but definitely needs a chain over his nose to be handled safely. He then begins eating his grain, but stops after a few bites, and begins to display some odd behavior. He stands in a very tense posture, frequently nods his head, mouths a lot, and appears to twitch in the shoulder/back area, as if he is trying to get flies off his back. His eyes somewhat glaze over, and he appears to be somewhat disconnected from the outside world, if that makes sense. He tends to turn his head to the right during these episodes, and will occasionally paw. The initial episodes in November and December, which were infrequent (less than 5 episodes per month) presented more as colics--he was treated for mild colic and each time had fairly dry manure and was mildly impacted, but responded well to treatment.

Throughout January and February, the episodes became more and more frequent, and for the past week they have occurred just about every other day. Interestingly, we do see them occasionally in the pasture, but always in the afternoons, so there does seem to be a link to the time of day, but the weather (sunny vs cloudy, etc) seems to have no effect. The vet has observed several of these episodes, and has come to believe that they are seizures. However, everyone is completely stumped as to the cause, and from the literature we've been able to find, these seem fairly unusual for seizures in horses.

He is going to the vet this afternoon for a spinal tap, as the current hope is that it is EPM. Other possibilities are epilepsy, encephalitis, brain tumor--not good stuff! One other possibility that has been raised is seizures related to Cushings--this horse doesn't present with other Cushings symptoms, but is a metabolic disorder type horse--no problems yet, but definitely the easy keeper profile until now. So, horse is under veterinary care, and the vet is consulting with other vets, but I'm wondering if anyone in this big group has ever seen something similar that we could look at. Link to the video below is from one of these episodes that occurred in the field last week--skip the first bit as you don't see much until a little bit into the video.

Thanks so much for any ideas!!

http://www.youtube.com/watch?v=w76j7PWQKi8

drifter99
Mar. 12, 2010, 07:53 PM
Have you done a good dental check on this horse? It could be a broken tooth, or something painful in his mouth.

Pookah
Mar. 12, 2010, 08:51 PM
Yes, I wish that was it, but already checked :-(. Thanks for the idea, though! One of the oddities is that dinner seems to trigger it but breakfast does not.

twofatponies
Mar. 12, 2010, 10:33 PM
The video is gone, but for what it's worth my mare had a seizure caused by a burst blood vessel caused by a brain tumor... unlike your case it was a more sudden onset - a huge seizure all at once.

But after she had stabilized and appeared to be fine again (ie the trauma of the initial bleed had subsided, which was about five days and several thousand dollars in IVs, sedatives and DMSO later), then gradually, after a month or so of seeming to have recovered (as the tumor continued to grow over the next month) she began to have mini-seizures again, increasing in frequency, and they varied in symptoms:

a sudden stopping, head raised, glazed eyes and twitching of the neck up and down; or a sudden stopping, hind legs stomping up and down for several seconds, eyes glazed; or a sudden weird spastic move, kind of like the way your body can jerk when you are falling asleep; shaking of just the right side of her muzzle, as if there was a fly there. Or a sudden weird posture, with her head raising straight up, nose to the sky, or combinations of these.

In between (and even during the first few days after her initial seizure, when she was very out of it and having ongoing symptoms) she would eat enthusiastically: eat eat eat spasm eat eat eat spasm. During the later recurring symptoms she was - in between the increasing moments of weirdness - cheerful, relaxed, and happy, eating well, etc.

Some of the things we ruled out (I sent her to Cornell as soon as she was stabilized enough to travel) that might have caused similar symptoms included:

every kind of spinal infectious disease, metabolic diseases, tick-borne diseases, abcesses or growths in the sinuses or ears that could press on the brain or nerves near the poll; off the top of my head those are the ones I recall...there's an old thread on her somewhere, if you search for "seizure"

When she initially seemed to be getting better the conclusion was brain bleed (burst blood vessel). But when the symptoms began to return and worsen day by day that left brain tumor.

So there is a long list of possibilities with your horse. If you are up for a lot of testing they can narrow it down pretty well, and I hope it turns out to be something simple and fixable!!

philosoraptor
Mar. 12, 2010, 11:08 PM
A local friend has a horse which has symptoms sounding similar to yours. The diagnosis ended up being brain tumor. :cry:

Pancakes
Mar. 12, 2010, 11:18 PM
If you're talking about diagnostics, ultimately the only way to visualize the brain is a CT or MRI (MRI is best). Otherwise, it's kind of guessing if the CSF tap comes back non-conclusive.

Sorry for your situation and your horse, and sorry I can't offer more help.

HappyTalk
Mar. 13, 2010, 07:28 PM
Any updates?

Auventera Two
Mar. 13, 2010, 08:49 PM
Last weekend I drove 2 1/2 hours to pick up a horse for a friend who was going to board at my house. He was a freebie - Impressive bred QH, 20 yr old, been-there, done-that, pleasure horse, drill team, trail, everything. HYPP negative - supposedly. He ended up having a massive seizure (episode??) as we were walking him toward the trailer. His right eye started twitching, which escalated to whole body tremors, facial paralysis, and eventually he became completely out of control and it was about 7 minutes of the scariest stuff I've ever seen. The vet came and drew new blood to test HYPP again, but if that is negative, then the diagnostics suggested were a general blood panel, CT scan, brain MRI, and radiographs. If the HYPP test comes back positive, we can manage that with diet, medication, and environment but if it indeed seizures, he will be euthanized.

This guy has had a couple of minor incidents where he got a little twitchy and zoned out, but nothing anywhere near to this magnitude. When the previous episodes happened, he had been severely malnourished so everyone thought it was due possibly to an electrolyte imbalance. Since there had been no occurances for years, everyone thought he would be fine. My friend was willing to take the chance and we really had no reason to believe it would happen again.

I'll be interested in this thread and what others suggest.

I'm really sorry about your horse :-(

dwblover
Mar. 13, 2010, 10:47 PM
Have you guys looked into EMND? (Equine Motor Neuron Disease). It's fairly rare but the symptoms could fit what you describe. I might also look into DSLD/ESPA as a possibility.

BuddyRoo
Mar. 14, 2010, 01:13 PM
I'm sure you've covered this base...but a fecal? Baylis ascaris procyonis AKA "racoon roundworm" can cause problems with vision and brain damage.

When my dog started having sudden onset of cluster seizures, that was one of the biggies we looked at.

Pookah
Mar. 14, 2010, 02:20 PM
Thanks so much for all of the ideas!! No real updates yet. We were supposed to take him in on Friday for a spinal tap, but the truck and trailer got completely stuck in the mud while we were getting ready to go, soooooooo that got moved to Monday!

He has continued to have episodes almost daily. We've additionally noticed that during the episodes, his neck seems painful, with tight muscles, and that he is unable to move his head downward.

So, on Monday he'll be getting the spinal tap plus more testing, hope that they are able to find something soon! His poor owner is being driven insane by the not-knowing of it.

twofatponies
Mar. 14, 2010, 03:07 PM
One suggestion from my experience is that if you bite the bullet and ship him to Cornell, Tufts or other similar veterinary hospital they can do *all* the testing in a few days flat, with immediate results. If you do them at home, you often have to wait a week for this one, a week or more for that one, etc. The tests are going to cost similar whether you do them at home or at a hospital; the extra costs at the hospital will be the "board" ($80 a day maybe?) and the shipping ("free" if you can trailer him, several hundred and up if you have to hire a shipper).

It would probably be worth it to get to an answer fast. Moreover, if he has a more serious attack, he will be in a padded stall surrounded by dozens of highly qualified personnel.